CELSR3/Flamingo homolog 1 Antibody
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Catalog number
bs-11460R
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Price
Please ask
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Size
0.1ml
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Long name
CELSR3/Flamingo homolog 1 Antibody
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Also known as
CELSR3/Flamingo homolog 1 Antibody
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
CELSR3/Flamingo homolog 1
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Specificity
This is a highly specific antibody against CELSR3/Flamingo homolog 1.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Polyclonal antibody
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Clone number
Polyclonal antibody
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Concentration
1ug per 1ul
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Immunogen range
1600-1650/3312
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Subcellular location
Extracellular
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Flamingo homolog 1
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Gene ID number
1951
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Swiss Prot
Q9NYQ7
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Tested Applications
IHC-P, IF(IHC-P)
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Recommended dilutions
IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
Drosophila Flamingo is a seven pass transmembrane cadherin that is necessary for dendritic patterning and axon guidance. Flamingo mammalian homo-logs play similar roles in neuronal development, during which they play an important role in cell-cell signaling. Cadherin EGF LAG seven pass G-type receptors (CELSRs) are multi-pass membrane proteins that belong to the G protein-coupled receptor family of proteins. Silencing CELSR2 gene ex-pression results in signficant simplification of dendritic arbors of cortical pyramidal neurons and Purkinje neurons, which may be due to branch retraction. In mouse, CELSR1, CELSR2 and CELSR3 are expressed in the nervous system at early developmental stages, and show expression patterns in the developing CNS. CELSR2 is distributed at intercellular boundaries in the whisker and on processes of neuronal cells such as hippocampal pyramidal cells, Purkinje cells and olfactory neurons.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
Cadherin EGF LAG seven-pass G-type receptor 3; Cadherin family member 11; CDHF11; CELR3_HUMAN; CELSR3; EGF-like protein 1; EGFL1; Epidermal growth factor-like protein 1; Flamingo; Flamingo homolog 1; FMI1; HFMI1; MEGF2; Multiple EGF-like domains protein 2; Multiple epidermal growth factor-like domains protein 2.
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
LINC02585, CELSR3
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Short name
Anti-CELSR3/Flamingo homolog 1
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Technique
Antibody, antibodies against human proteins, antibodies for
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Host
Rabbit (Oryctolagus cuniculus)
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Isotype
Immunoglobulin G (IgG)
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Alternative name
CELSR3/Flamingo homolog 1 Antibody
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Alternative technique
antibodies
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Alternative to gene target
cadherin, EGF LAG seven-pass G-type receptor 3 (flamin this GO homolog, Drosophila), CDHF11 and EGFL1 and FMI1 and HFMI1 and MEGF2 and RESDA1, CELSR3 and IDBG-33330 and ENSG00000008300 and 1951, protein binding, Plasma membranes, Celsr3 and IDBG-200591 and ENSMUSG00000023473 and 107934, CELSR3 and IDBG-646101 and ENSBTAG00000021846 and 100849387,523793
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Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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