Human CellExp™ Human CD40/ TNFRSF5, Human recombinant

  • Catalog number
    9230-50
  • Price
    Please ask
  • Size
    50 µg
  • Synonyms
    CD40, Bp50, CDW40, MGC9013, TNFRSF5, p51
  • Alternative_names
    CD40, Bp50, CDW40, MGC9013, TNFRSF5, p51
  • Description
    Tumor necrosis factor receptor superfamily member 5
  • Recombinant
    Yes
  • Source
    HEK 293 cells
  • Purity by SDS PAGE
    >95%
  • Assay
    SDS-PAGE
  • Purity
    >95%
  • Endotoxin Level
    < 1 EU/ug
  • Activity Specifications test method
    Measured by its binding ability in a functional ELISA.
  • Biological activity
    Immobilized Human CD40, His Tag at 1 µg/mL (100 µL/well) can bind Human CD40 Ligand /TNFSF5 with a linear range of 0.01-0.12 ng/mL.
  • Binding Capacity
    Immobilized Human CD40, His Tag at 1 µg/mL (100 µL/well) can bind Human CD40 Ligand /TNFSF5 with a linear range of 0.01-0.12 ng/mL.
  • Molecular Weight
    This protein is fused with a 6× His tag at C-terminus and has a calculated MW of 20 kDa. The protein migrates as 32 kDa in SDS-PAGE due to glycosylation.
  • Storage Temp
    -20°C
  • Shipping
    Gel pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized
  • Physical form description
    Lyophilized from 0.22 um filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.
  • Reconstitution Instructions
    Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 ug/ml
  • Background Information
    Tumor necrosis factor receptor superfamily member 5 (TNFRSF5) is also known as CD40, is a member of the TNF receptor superfamily. The expression of CD40 is diverse. TNFRSF5 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is the receptor for TNFSF5/CD40LG. Defects in CD40 are the cause of immunodeficiency with hyper-IgM type 3 (HIGM3).
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    CD40
  • Short name
    CellExp™ CD40/ TNFRSF5, recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Humans
  • Alternative name
    H. sapiens CellExp™ H. sapiens CD40 molecule, tumor necrosis factor receptor superfamily member 5/ TNFRSF5, H. sapiens Rec.
  • Alternative technique
    rec
  • Alternative to gene target
    CD40 molecule, TNF receptor superfamily member 5, Bp50 and CDW40 and p50 and TNFRSF5, CD40 and IDBG-78904 and ENSG00000101017 and 958, ubiquitin protein ligase binding, Extracellular, Cd40 and IDBG-212533 and ENSMUSG00000017652 and 21939, BT.42498 and IDBG-643036 and ENSBTAG00000020736 and 286849
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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