Human CellExp™ HGH, Human Recombinant

• Catalog number
  6457-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  Human Cellexp Human Recombinant HGH
• Alternative_names
  Human Growth Hormone, GH1, GH, GHN, GH-N, hGH-N, Pituitary growth hormone, Growth hormone 1, Somatotropin.
• Description
  A protein which plays an important role in growth control
• Recombinant
  Yes
• Source
  Human 293 cell expressed
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1.0 EU per 1 ug of protein
• Biological activity
  ED₅₀ is typically 0.4 to 2 ng/mL. The activity was determined by the dose-dependent stimulation of the proliferation of rat lymphoma line Nb2-11 cells (prolactin indicator cell line).
• Results
  0.4 to 2 ng/ml
• Molecular Weight
  22 kDa, monomer, non-glycosylated
• Storage Temp
  -20°C
• Shipping
  gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from a TBS solution.
• Reconstitution Instructions
  Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
• Background Information
  HGH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. HGH can promote bone and cartilage growth as well as increase protein synthesis through liver somatomedin and tissue polypeptide growth factor, correct the post-traumatic state of negative nitrogen and hypoproteinemia induced by severe infection and cirrhosis; stimulate immunoglobulin synthesis, stimulate the proliferation of lymphoid tissue, macrophages and lymphocyte, and accelerate wound healing; promote myocardial protein synthesis, increase myocardial contractility and reduce myocardial oxygen consumption; regulating fat metabolism, reducing serum cholesterol, low - density lipoprotein level.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   HGH  
• Gene symbol
  GH1, GH2
• Short name
  CellExp™ HGH, Recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ HGH, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:4261
• Gene
  GH1
• Long gene name
  growth hormone 1
• Synonyms
  • GH-N
  • GHN
  • GH
  • hGH-N
• Synonyms name
  • pituitary growth hormone
  • somatotropin
• GenBank acession
  • M13438
• Locus
  17q23.3
• Discovery year
  2001-06-22
• Entrez gene record
  2688
• Pubmed identfication
  • 6306568
• RefSeq identity
  • NM_000515
• Classification
  • Growth hormone family
• VEGA ID
  OTTHUMG00000172293

Gene info

• Identity
  HGNC:4262
• Gene
  GH2
• Long gene name
  growth hormone 2
• Synonyms
  • GH-V
  • GHV
  • GHL
  • hGH-V
• Synonyms name
  • placental-specific growth hormone
  • placenta-specific growth hormone
• GenBank acession
  • J03756
• Locus
  17q23.3
• Discovery year
  2001-06-22
• Entrez gene record
  2689
• Pubmed identfication
  • 6306568
• RefSeq identity
  • NM_002059
• Classification
  • Growth hormone family
• VEGA ID
  OTTHUMG00000172284

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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