RAD51(Tyr315) Antibody, ALEXA FLUOR 350

• Catalog number
  bs-5684R-A350
• Price
  Please ask
• Size
  100ul

• Long name
  RAD51(Tyr315) Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
• Also known as
  Anti-RAD51 Tyr315 PAb ALEXA FLUOR 350
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 350
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  RAD51 Tyr315
• Specificity
  This is a highly specific antibody against RAD51 Tyr315.
• Modification
  Phosphorylation
• Modification Site
  Tyr315
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human RAD51 around the phosphorylation site of Tyr315
• Gene ID Number
  5888
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. Transcript variants utilizing alternative polyA signals exist.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  343nm/442nm
• Synonyms
  RAD51phospho Y315; BRCA1/BRCA2 containing complex, subunit 5; BRCC 5; BRCC5; DNA repair protein RAD51 homolog 1; DNA repair protein rhp51; E coli RecA homolog; HGNC:9817; Homolog of E coli RecA; homolog of S cerevisiae RAD51; HRAD51; HsRad51; HsT16930; Rad 51; RAD51 homolog RecA homolog, E. coli S. cerevisiae; RAD51 homolog; RAD51 homolog S. cerevisiae; RAD51 S cerevisiae homolog; RAD51A; RECA; RecA homolog E. coli; RecA like protein; RecA, E. coli, homolog of; recombination protein A.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 350
• French translation
  anticorps

• Gene target
  RAD51   Tyr315  
• Gene symbol
  RAD51-AS1, RAD51
• Short name
  Anti-RAD51 Tyr315
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 350
• Alternative name
  RAD51(Tyr315) Polyclonal Antibody, ALEXA FLUOR 350
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:48621
• Gene
  RAD51-AS1
• Long gene name
  RAD51 antisense RNA 1
• Synonyms gene name
  • RAD51 antisense RNA 1 (head to head)
• Synonyms
  • TODRA
• Synonyms name
  • transcribed in the opposite direction of RAD51
• GenBank acession
  • AK125393
• Locus
  15q15.1
• Discovery year
  2013-05-24
• Entrez gene record
  100505648
• Pubmed identfication
  • 26230935
• RefSeq identity
  • NR_040058
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000166119

Gene info

• Identity
  HGNC:9817
• Gene
  RAD51
• Long gene name
  RAD51 recombinase
• Synonyms gene
  • RAD51A
  • RECA
• Synonyms gene name
  • RAD51 (S. cerevisiae) homolog (E coli RecA homolog)
  • RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
  • RAD51 homolog (S. cerevisiae)
• Synonyms
  • HsRad51
  • HsT16930
  • BRCC5
  • FANCR
• Synonyms name
  • BRCA1/BRCA2-containing complex, subunit 5
• GenBank acession
  • D13804
• Locus
  15q15.1
• Discovery year
  1993-05-26
• Entrez gene record
  5888
• Pubmed identfication
  • 8358431
  • 8479919
  • 26253028
• RefSeq identity
  • NM_002875
  • NM_133487
• Classification
  • FA complementation groups
• VEGA ID
  OTTHUMG00000130067
• Locus Specific Databases
  • Fanconi Anaemia Mutation Database
  • LRG_313

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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