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SirtACt for cell activation

SirtACt for cell activation is available 2 times from Biovision labs

2741-2 | SirtACt for cell activation size: 2 mg | 173.59 USD

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2741-10 | SirtACt for cell activation size: 10 mg | 519.65 USD

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Other name 2-​Amino-​N-​cyclopentyl-​1-​(3-​methoxypropyl)-​1H-​pyrrolo[2,​3-​b]quinoxaline-​3-​carboxamide; CAY10591; SIRT1 activator 3; Sirtuin1 Activator 3
Supplied with N/A
Description SirtAct is a potent Sirtuin 1 (SIRT1) activator. It increases fluorescence by 233% in a SIRT1 activity assay. SIRT1 stimulation by SirtAct leads to decreased tissue factor mediated thrombogenicity in mice. It inhibits NF-κB activation and reduces inflammatory cytokine production in lamina propria mononuclear cells from IBD patients. SirtAct also prevents and cures experimental colitis in a mouse model.
Category Biochemicals
Molecular formula C₂₀H₂₅N₅O₂
Is it cell-permeable? Yes
Molecular weight 367.5
Storage condition -20°C
Shipping condition Gel Pack
Purification ≥98% by TLC
Peptide sequence N/A
Is this a salt? No
CAS number 839699-72-8
Storage instructions Protect from air and light
Maximum time for storage 36 months
Physical appearance Olive green solid
Reconstitute instructions DMSO (50 mg/ml) or EtOH (20 mg/ml, warm)
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetSirtACt for activation
Short name SirtACt for activation
Technique activation
Alternative name SirtACt to measure cellular activation
Tissue cell
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