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IL1RN IL-1 Receptor Antagonist Protein IL-1ra IL-1RN IRAP IL1 Inhibitor ICIL-1RA Anakinra IL1RA IL1F3

IL1RN IL-1 Receptor Antagonist Protein IL-1ra IL-1RN IRAP IL1 Inhibitor ICIL-1RA Anakinra IL1RA IL1F3 is available 2 times from Mbs monoclonals labs

GEN632640 | IL1RN (IL-1 Receptor Antagonist Protein, IL-1ra, IL-1RN, IRAP, IL1 Inhibitor, ICIL-1RA, Anakinra, IL1RA, IL1F3) size: 100ug | 645.64 USD

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GEN632640 | IL1RN (IL-1 Receptor Antagonist Protein, IL-1ra, IL-1RN, IRAP, IL1 Inhibitor, ICIL-1RA, Anakinra, IL1RA, IL1F3) Antibody size: 100ug | 645.64 USD

Catalog number GEN632640
Price 645.64 USD
Size 100ug
Description The antagonist receptor ligand binding will be in contrast with agonist activity. MBS Monoclonals produces more antagonist and receptor related products as 1.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Properties If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Gene The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
French translation anticorps
Short name IL1RN (IL-1 Receptor Antagonist Protein, IL-1ra, IL-1RN, IRAP, IL1 Inhibitor, ICIL-1RA, Anakinra, IL1RA, IL1F3) Antibody
Technique Antibody
Alternative technique antibodies
1. Gene info
Identity 6000
Gene IL1RN
Long gene name interleukin 1 receptor antagonist
Synonyms
  • IL1RA
  • ICIL-1RA
  • IL1F3
  • IRAP
  • IL-1RN
  • MGC10430
Synonyms name
  • interleukin-1 receptor antagonist protein
  • intracellular interleukin-1 receptor antagonist
GenBank acession
  • M55646
Locus 2q14.1
Discovery year 1990-11-20
Entrez gene record 3557
Pubmed identfication
  • 1386337
  • 8432529
RefSeq identity
  • NM_173841
Classification
  • Interleukin receptors
  • Interleukins
Havana BLAST/BLAT OTTHUMG00000131341
Locus Specific Databases
  • LRG_188
2. Gene info
Identity 5993
Gene IL1R1
Long gene name interleukin 1 receptor type 1
Synonyms gene
  • IL1R
  • IL1RA
Synonyms gene name
  • interleukin 1 receptor, type I
Synonyms
  • D2S1473
  • CD121A
Synonyms name
  • interleukin-1 receptor, type I
GenBank acession
  • M27492
Locus 2q11.2-q12.1
Discovery year 1990-06-27
Entrez gene record 3554
Pubmed identfication
  • 1833184
  • 10191101
Classification
  • CD molecules
  • Interleukin receptors
  • TIR domain containing
  • I-set domain containing
Havana BLAST/BLAT OTTHUMG00000130783
3. Gene info
Identity 5990
Gene IL19
Long gene name interleukin 19
Synonyms
  • IL-19
  • MDA1
  • ZMDA1
  • IL-10C
  • NG.1
Synonyms name
  • melanoma differentiation associated protein-like protein
GenBank acession
  • AF192498
Locus 1q32.1
Discovery year 2000-03-29
Entrez gene record 29949
Pubmed identfication
  • 11196675
RefSeq identity
  • NM_153758
Classification
  • Interleukins
Havana BLAST/BLAT OTTHUMG00000036387
4. Gene info
Identity 6656
Gene LNPEP
Long gene name leucyl and cystinyl aminopeptidase
Synonyms gene name
  • leucyl/cystinyl aminopeptidase
Synonyms
  • CAP
  • PLAP
  • P-LAP
  • IRAP
Synonyms name
  • cystinyl aminopeptidase
  • placental leucine aminopeptidase
GenBank acession
  • D50810
Locus 5q15
Discovery year 1997-07-11
Entrez gene record 4012
Pubmed identfication
  • 8550619
RefSeq identity
  • NM_005575
Classification
  • Aminopeptidases
  • M1 metallopeptidases
Havana BLAST/BLAT OTTHUMG00000128719
5. Gene info
Identity 13765
Gene IL25
Long gene name interleukin 25
Synonyms gene
  • IL17E
Synonyms gene name
  • interleukin 17E
Synonyms
  • IL-25
  • IL-17E
GenBank acession
  • AF305200
Locus 14q11.2
Discovery year 2001-01-26
Pubmed identfication
  • 11058597
  • 11754819
Classification
  • Interleukins
Havana BLAST/BLAT OTTHUMG00000028749
6. Gene info
Identity 5991
Gene IL1A
Long gene name interleukin 1 alpha
Synonyms gene
  • IL1
Synonyms
  • IL1F1
  • IL-1A
  • IL1-ALPHA
Synonyms name
  • preinterleukin 1 alpha
  • hematopoietin-1
  • pro-interleukin-1-alpha
GenBank acession
  • M28983
Locus 2q14.1
Discovery year 2001-06-22
Entrez gene record 3552
Pubmed identfication
  • 8188271
  • 2989698
RefSeq identity
  • NM_000575
Classification
  • Interleukins
Havana BLAST/BLAT OTTHUMG00000131315
Also known as IL1RN
Other names interleukin-1 receptor antagonist protein isoform 4; Interleukin-1 receptor antagonist protein; interleukin-1 receptor antagonist protein; IL1 inhibitor; IL1RN (IL1F3); type II interleukin-1 receptor antagonist; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); interleukin 1 receptor antagonist; ICIL-1RA; IL1 inhibitor
Category Antibodies
Subcategory Mnoclonal antibodies
Gene name IL1RN; IL1RN; DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA; IL1F3; IL1RA; IL-1RN; IL-1ra; IRAP
Gene name synonims IL1RN; IL1RN; DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA; IL1F3; IL1RA; IL-1RN; IL-1ra; IRAP
Other gene names IL1RN; IL1RN; DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA; IL1F3; IL1RA; IL-1RN; IL-1ra; IRAP
Clonality Monoclonal
Immunoglobulin isotype IgG1
Clone 10K255
Host organism Mouse (Mus musculus)
Source organism Human (Homo sapiens)
Species reactivity Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity Recognizes human IL1RN.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Purification method Affinity Purified by Protein A affinity chromatography.
Form/Appearance Supplied as a liquid in PBS, 0.1% sodium azide.
Concentration N/A
Storage and shipping Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Tested applications: ELISA (EL/EIA)
Gene targetIL1RN IL-1 Receptor Antagonist Protein IL-1ra IL-1RN IRAP IL1 Inhibitor ICIL-1RA Anakinra IL1RA IL1F3
Alternative name Anti-IL1RN (Interleukin-1 Receptor Antagonist Protein, IL-1ra, IL-1RN, IRAP, IL1 Inhibitor, ICIL-1RA, Anakinra, IL1RA, IL1F3)
Alternative to gene target interleukin 1 receptor anta this GO nist, DIRA and ICIL-1RA and IL-1ra and IL-1ra3 and IL-1RN and IL1F3 and IL1RA and IRAP and MVCD4, IL1RN and IDBG-66814 and ENSG00000136689 and 3557, interleukin-1, Extracellular, Il1rn and IDBG-142372 and ENSMUSG00000026981 and 16181, IL1RN and IDBG-634670 and ENSBTAG00000019665 and 281860
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IL1RN (IL-1 Receptor Antagonist Protein, IL-1ra, IL-1RN, IRA
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EU:+32-(0)1-658-90-45 US:+1-(408)780-0908 [email protected]
  • IL1RN
  • IL-1
  • Receptor
  • Antagonist
  • Protein
  • IL-1ra
  • IL-1RN
  • IRAP
  • IL1
  • Inhibitor
  • ICIL-1RA
  • Anakinra
  • IL1RA
  • IL1F3
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