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Target antigen
Peroxiredoxin 6
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
human
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Analyses
WB,IHC-P
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Immunogen
E.coli-derived human Peroxiredoxin 6 recombinant protein (Position: E15-P224). Human Peroxiredoxin 6 shares 90% and 91% amino acid (aa) sequence identity with mouse and rat Peroxiredoxin 6, respectively.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the Peroxiredoxin 6 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The Peroxiredoxin 6 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
PRDX6 is also known as PRX, p29 or AOP2. The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
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Related articles
1. Ambruso DR, et al. Peroxiredoxin 6 translocates to the plasma membrane during neutrophil activation and is required for optimal NADPH oxidase activity. Biochim Biophys Acta, 2012 Feb. 2. Chhunchha B, et al. Aberrant sumoylation signaling evoked by reactive oxygen species impairs protective function of Prdx6 by destabilization and repression of its transcription. FEBS J, 2014 Aug. 3. Guo HW, et al. Expression of peroxiredoxin 6 in gastric cancer and its clinical significance. Zhonghua Yi Xue Za Zhi, 2012 Sep 11.
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Gene Name
PRDX6
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Protein Name
Peroxiredoxin-6
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Gene Full Name
peroxiredoxin 6
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Synonyms
1 Cys antibody|1 Cys peroxiredoxin antibody|1 Cys PRX antibody|1 cysPrx antibody|1-Cys peroxiredoxin antibody|1-Cys PRX antibody|24 kDa protein antibody|9430088D19Rik antibody|AA690119 antibody|Acidic calcium independent phospholipase A2 antibody|Acidic calcium-independent phospholipase A2 antibody|aiPLA2 antibody|Antioxidant protein 2 antibody|AOP2 antibody|Aop2 rs3 antibody|Brp 12 antibody|Ciliary body glutathione peroxidase antibody|CP 3 antibody|EC 1.11.1.15 antibody|EC 1.11.1.7 antibody|EC 3.1.1. antibody|GPx antibody|KIAA0106 antibody|Liver 2D page spot 40 antibody|Ltw4 antibody|Lvtw 4 antibody|MGC46173 antibody|mKIAA0106 antibody|Non selenium glutathione peroxidase antibody|Non-selenium glutathione peroxidase antibody|NSGPx antibody|ORF06 antibody|OTTHUMP00000032693 antibody|p29 antibody|Peroxiredoxin-6 antibody|Peroxiredoxin6 antibody|PHGPx antibody|Phospholipase A2 lysosomal antibody|PLA2 antibody|PRDX 6 antibody|Prdx5 antibody|PRDX6 antibody|Prdx6 rs3 antibody|PRDX6_HUMAN antibody|PRX antibody|Red blood cells page spot 12 antibody|Thiol specific antioxidant protein antibody
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Uniprot ID
P30041
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Entrez GeneID
9588
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
