Human CellExp™ CD48 / BCM1 / SLAMF2, human recombinant

• Catalog number
  7380-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  CD48, BCM1, SLAMF2, BLAST1, BLAST, BLAST1, MEM-102, TCT.1, BCM-1, SLAMF-2, BLAST-1
• Alternative_names
  CD48, BCM1, SLAMF2, BLAST1, BLAST, BLAST1, MEM-102, TCT.1, BCM-1, SLAMF-2, BLAST-1
• Description
  Facilitates interaction between activated lymphocytes
• Recombinant
  Yes
• Source
  HEK293 cells
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Biological activity
  Measured by its binding ability in a functional ELISA. Immobilized human CD244 protein Fc Chimera at 5 ug/ml (100 ul/well) can bind human CD48 with a linear range of 0.1 - 4 ug/ml.
• Results
  Measured by its binding ability in a functional ELISA. Immobilized human CD244 protein Fc Chimera at 5 ug/ml (100 ul/well) can bind human CD48 with a linear range of 0.1 - 4 ug/ml.
• Molecular Weight
  This protein is fused with 6×His tag at the C-terminus, has a calculated MW of 23.2 kDa. The predicted N-terminus is Gln 27. DTT-reduced Protein migrates as 38-45 kDa due to glycosylation.
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
• Reconstitution Instructions
  Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
• Background Information
  CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   CD48   BCM1   SLAMF2  
• Gene symbol
  CD48
• Short name
  CellExp™ CD48 / BCM1 / SLAMF2, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ CD48 molecule / BCM1 / SLAMF2, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  CD48 molecule, BCM1 and BLAST and BLAST1 and hCD48 and mCD48 and MEM-102 and SLAMF2, CD48 and IDBG-104080 and ENSG00000117091 and 962, protein binding, Cell surfaces, Cd48 and IDBG-204791 and ENSMUSG00000015355 and 12506, CD48 and IDBG-630526 and ENSBTAG00000011238 and 508386

Gene info

• Identity
  HGNC:1683
• Gene
  CD48
• Long gene name
  CD48 molecule
• Synonyms gene
  • BCM1
• Synonyms gene name
  • CD48 antigen (B-cell membrane protein)
  • CD48 molecule
• Synonyms
  • BLAST
  • mCD48
  • hCD48
  • SLAMF2
• GenBank acession
  • BC016182
• Locus
  1q23.3
• Discovery year
  1986-01-01
• Entrez gene record
  962
• Pubmed identfication
  • 2828034
• RefSeq identity
  • NM_001778
• Classification
  • V-set domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000024009

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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