NFKB Inhibitor Interacting Ras-Like 2 Protein (Recombinant)

• Catalog number
  abx262515
• Price
  Please ask
• Size
  1 mg

• Category
  Proteins And Peptides
• Clonality
  N/A
• Raised in
  N/A
• Target
  Like 2 Protein
• Immunogen
  see included datasheet or contact us
• Species reactivity
  Human, Mouse, Rat (for other species please inquire)
• Purification
  Affinity purified
• Applications
  WB (for other applications please contact us)
• Stock availability
  Shipped within 5-10 working days.
• Storage conditions
  Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
• Footnote
  This product is for research use only.
• Other products
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
• Gene
  NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  NFKB   Inhibitor   Interacting   Ras-Like   Protein  
• Gene symbol
  NFKB1
• Short name
  NFKB Inhibitor Interacting Ras-Like 2 Protein (Recombinant)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Abbexa advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Label
  Unconjugated
• Alternative name
  NFKB suppressor Interacting Ras-Like 2 Protein (Rec.)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:7794
• Gene
  NFKB1
• Long gene name
  nuclear factor kappa B subunit 1
• Synonyms gene name
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
• Synonyms
  • KBF1
  • p105
  • NFKB-p50
  • p50
  • NF-kappaB
  • NFkappaB
  • NF-kB1
• Synonyms name
  • Nuclear factor NF-kappa-B p105 subunit
• GenBank acession
  • M58603
• Locus
  4q24
• Discovery year
  1991-11-14
• Entrez gene record
  4790
• Pubmed identfication
  • 1992489
• RefSeq identity
  • NM_003998
• Classification
  • NF-kappa B complex subunits
  • Ankyrin repeat domain containing
  • IPT domain containing
• VEGA ID
  OTTHUMG00000161080
• Locus Specific Databases
  • LRG_1316

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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