Bone Morphogenetic Protein Receptor Type 1B (BMPR-IB, BMPR1B, BR1b, BMP Type-1B Receptor, Receptor-like Kinase 6, ALK6, ALK-6, CDw293) (APC) Antibody

• Catalog number
  GEN632595
• Price
  Please ask
• Size
  100 Tests

• Also known as
  Bone Morphogenetic Protein Receptor Type 1B
• Other names
  bone morphogenetic protein receptor type-1B isoform b; Bone morphogenetic protein receptor type-1B; bone morphogenetic protein receptor type-1B; BMPR-1B; BMP type-1B receptor; activin receptor-like kinase 6; serine/threonine receptor kinase; bone morphogenetic protein receptor, type IB; N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  BMPR1B; BMPR1B; ALK6; ALK-6; CDw293; BMP type-1B receptor; BMPR-1B
• Gene name synonims
  BMPR1B; BMPR1B; ALK6; ALK-6; CDw293; BMP type-1B receptor; BMPR-1B
• Other gene names
  BMPR1B; BMPR1B; ALK6; ALK-6; CDw293; BMP type-1B receptor; BMPR-1B
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2b
• Clone
  11C3
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes human BMPR-IB.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein G affinity chromatography.
• Form Appearance
  Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
• Concentration
  N/A
• Storage and shipping
  May be stored at Store the antibody at +4 degrees Celsius. before opening. DO NOT FREEZE! Stable at Keep the antibody refrigerated at +4 degrees Celsius. Temperature variations in the range between +1C to +7C are tolerable. Stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Freezing Labeled with Allophycocyanin (APC) conjugates will result in a substantial loss of activity. Further dilutions can be made in assay buffer. APC is light sensitive.
• Tested applications
  Flow Cytometry (FC/FACS)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  Bone   Morphogenetic   Protein   Receptor   BMPR-IB   BMPR1B   BR1b   BMP   Receptor   Receptor-like   Kinase   ALK6   ALK-6   CDw293   APC  
• Gene symbol
  BMPR1B, BMPR1B-DT, BMPR2, ALK, GDF11, GDF10, NT5C1B, ENPP7, APC, BMP1
• Short name
  Bone Morphogenetic Protein Receptor 1B (BMPR-IB, BMPR1B, BR1b, BMP -1B Receptor, Receptor-like Kinase 6, ALK6, ALK-6, CDw293) (APC) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Label
  APC
• Alternative name
  Anti-Bone Morphogenetic Protein Receptor Type 1B (BMPR-IB, BMPR1B, BR1b, BMP Type-1B Receptor, Receptor-like Kinase 6, ALK6, ALK-6, CDw293) (APC)
• Alternative technique
  antibodies
• Alternative to gene target
  bone morphogenetic protein receptor, type IB, ALK-6 and ALK6 and CDw293, BMPR1B and IDBG-30667 and ENSG00000138696 and 658, transforming growth factor beta receptor activity, Plasma membranes, Bmpr1b and IDBG-196928 and ENSMUSG00000052430 and 12167, BMPR1B and IDBG-641011 and ENSBTAG00000002081 and 407128
• Tissue
  bone

Gene info

• Identity
  HGNC:1077
• Gene
  BMPR1B
• Long gene name
  bone morphogenetic protein receptor type 1B
• Synonyms gene name
  • bone morphogenetic protein receptor, type IB
• Synonyms
  • ALK6
  • CDw293
• GenBank acession
  • D89675
• Locus
  4q22.3
• Discovery year
  1997-03-19
• Entrez gene record
  658
• Pubmed identfication
  • 8140412
  • 9730621
• RefSeq identity
  • NM_001203
• Classification
  • CD molecules
  • Type 1 receptor serine/threonine kinases
• VEGA ID
  OTTHUMG00000130991

Gene info

• Identity
  HGNC:50864
• Gene
  BMPR1B-DT
• Long gene name
  BMPR1B divergent transcript
• Synonyms gene
  • BMPR1B-AS1
• Synonyms gene name
  • BMPR1B antisense RNA 1 (head to head)
• Synonyms
  • TCONS_00007797
• Locus
  4q22.3
• Discovery year
  2014-07-14
• Entrez gene record
  100507012
• Classification
  • Divergent transcripts
• VEGA ID
  OTTHUMG00000161193

Gene info

• Identity
  HGNC:1078
• Gene
  BMPR2
• Long gene name
  bone morphogenetic protein receptor type 2
• Synonyms gene
  • PPH1
• Synonyms gene name
  • primary pulmonary hypertension 1
  • bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • bone morphogenetic protein receptor type II
• Synonyms
  • BRK-3
  • T-ALK
  • BMPR3
  • BMPR-II
• GenBank acession
  • Z48923
• Locus
  2q33.1-q33.2
• Discovery year
  1997-03-19
• Entrez gene record
  659
• Pubmed identfication
  • 7791754
• RefSeq identity
  • NM_001204
• Classification
  • Type 2 receptor serine/threonine kinases
• VEGA ID
  OTTHUMG00000133617
• Locus Specific Databases
  • LRG_712

Gene info

• Identity
  HGNC:427
• Gene
  ALK
• Long gene name
  ALK receptor tyrosine kinase
• Synonyms gene name
  • anaplastic lymphoma kinase (Ki-1)
  • anaplastic lymphoma receptor tyrosine kinase
• Synonyms
  • CD246
  • ALK1
• GenBank acession
  • D45915
• Locus
  2p23.2-p23.1
• Discovery year
  1993-08-24
• Entrez gene record
  238
• Pubmed identfication
  • 8122112
• RefSeq identity
  • NM_004304
• Classification
  • Receptor tyrosine kinases
  • CD molecules
• VEGA ID
  OTTHUMG00000152034
• Locus Specific Databases
  • LRG_488

Gene info

• Identity
  HGNC:4216
• Gene
  GDF11
• Long gene name
  growth differentiation factor 11
• Synonyms
  • BMP-11
  • BMP11
• GenBank acession
  • AF100907
• Locus
  12q13.2
• Discovery year
  1999-12-02
• Entrez gene record
  10220
• Pubmed identfication
  • 15988002
• Classification
  • Transforming growth factor beta superfamily
• VEGA ID
  OTTHUMG00000170188

Gene info

• Identity
  HGNC:4215
• Gene
  GDF10
• Long gene name
  growth differentiation factor 10
• Synonyms
  • BMP-3b
• GenBank acession
  • L42113
• Locus
  10q11.22
• Discovery year
  1997-09-12
• Entrez gene record
  2662
• Pubmed identfication
  • 8679252
• RefSeq identity
  • NM_004962
• Classification
  • Transforming growth factor beta superfamily
• VEGA ID
  OTTHUMG00000188319

Gene info

• Identity
  HGNC:17818
• Gene
  NT5C1B
• Long gene name
  5'-nucleotidase, cytosolic IB
• Synonyms
  • AIRP
  • CN-IB
• GenBank acession
  • AF356185
• Locus
  2p24.2
• Discovery year
  2002-04-18
• Entrez gene record
  93034
• Pubmed identfication
  • 11690631
• Classification
  • 5'-nucleotidases
• VEGA ID
  OTTHUMG00000151765

Gene info

• Identity
  HGNC:23764
• Gene
  ENPP7
• Long gene name
  ectonucleotide pyrophosphatase/phosphodiesterase 7
• Synonyms
  • alk-SMase
  • NPP7
• Synonyms name
  • alkaline sphingomyelinase
• GenBank acession
  • AY230663
• Locus
  17q25.3
• Discovery year
  2004-04-29
• Entrez gene record
  339221
• Pubmed identfication
  • 12885774
• RefSeq identity
  • NM_178543
• Classification
  • Ectonucleotide pyrophosphatase/phosphodiesterase family
• VEGA ID
  OTTHUMG00000177462

Gene info

• Identity
  HGNC:583
• Gene
  APC
• Long gene name
  APC regulator of WNT signaling pathway
• Synonyms gene name
  • adenomatosis polyposis coli
  • adenomatous polyposis coli
  • APC, WNT signaling pathway regulator
• Synonyms
  • DP2
  • DP3
  • DP2.5
  • PPP1R46
• Synonyms name
  • protein phosphatase 1, regulatory subunit 46
• GenBank acession
  • M74088
• Locus
  5q22.2
• Discovery year
  1986-01-01
• Entrez gene record
  324
• Pubmed identfication
  • 1651563
• RefSeq identity
  • NM_000038
• Classification
  • Protein phosphatase 1 regulatory subunits
  • Armadillo repeat containing
• VEGA ID
  OTTHUMG00000128806
• Locus Specific Databases
  • Adenomatous polyposis coli mutation database
  • UMD Locus Specific Databases
  • Global Variome shared LOVD
  • APC database at LOVD-China
  • LOVD - Leiden Open Variation Database
  • LRG_130

Gene info

• Identity
  HGNC:1067
• Gene
  BMP1
• Long gene name
  bone morphogenetic protein 1
• Synonyms gene
  • PCOLC
• Synonyms gene name
  • procollagen C-endopeptidase
• Synonyms
  • BMP-1
• Synonyms name
  • procollagen C-endopeptidase
  • tolloid-like
• Locus
  8p21.3
• Discovery year
  1990-06-11
• Entrez gene record
  649
• Pubmed identfication
  • 2004778
• RefSeq identity
  • NM_006132
• Classification
  • Bone morphogenetic proteins
  • Astacins
• VEGA ID
  OTTHUMG00000097761

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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