GLX-351322

  • Catalog number
    B2340-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    Ethyl 2-[[2-[4-(furan-2-carbonyl)piperazin-1-yl]acetyl]amino]-5,6-dihydro-4H-cyclopenta-[b]thiophene-3-carboxylate,GLX351322
  • Description
    GLX-351322 is a potent NADPH oxidase-4 (NOX-4) inhibitor. Displays selectivity for NOX-4 over NOX-2. GLX-351322 inhibits hydrogen peroxide production from tetracycline inducible NOX4-overexpressing cells (IC₅₀ = 5 µM).
  • CAS Number
    835598-94-2
  • Structure Available
    Yes
  • Molecular Formula
    C₂₁H₂₅N₃O₅S
  • Molecular Weight
    431.51
  • Cell Permeable
    1
  • Purity
    ≥98% by HPLC
  • Solubilities
    >5 mg/ml (DMSO)
  • Handling
    Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
  • Tag Line
    A NADPH oxidase 4 (NOX-4) inhibitor
  • Storage Condition
    -20ºC
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • PubChem CID
    2697686
  • SMILES
    CCOC(=O)C1=C(SC2=C1CCC2)NC(=O)CN3CCN(CC3)C(=O)C4=CC=CO4
  • InChi
    InChI=1S/C21H25N3O5S/c1-2-28-21(27)18-14-5-3-7-16(14)30-19(18)22-17(25)13-23-8-10-24(11-9-23)20(26)15-6-4-12-29-15/h4,6,12H,2-3,5,7-11,13H2,1H3,(H,22,25)
  • InChi Key
    KEVHLTCEMHIJTQ-UHFFFAOYSA-N
  • MSDS Available
    1
  • Gene target
  • Short name
    GLX-351322
  • Alternative name
    GLX-351322
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