GLX-351322
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Catalog numberB2340-25
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PricePlease ask
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Size25 mg
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Alternative_nameEthyl 2-[[2-[4-(furan-2-carbonyl)piperazin-1-yl]acetyl]amino]-5,6-dihydro-4H-cyclopenta-[b]thiophene-3-carboxylate,GLX351322
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DescriptionGLX-351322 is a potent NADPH oxidase-4 (NOX-4) inhibitor. Displays selectivity for NOX-4 over NOX-2. GLX-351322 inhibits hydrogen peroxide production from tetracycline inducible NOX4-overexpressing cells (IC₅₀ = 5 µM).
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CAS Number835598-94-2
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Structure AvailableYes
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Molecular FormulaC₂₁H₂₅N₃O₅S
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Molecular Weight431.51
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Cell Permeable1
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Purity≥98% by HPLC
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Solubilities>5 mg/ml (DMSO)
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HandlingDo not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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Tag LineA NADPH oxidase 4 (NOX-4) inhibitor
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Storage Condition-20ºC
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Shipping ConditionGel Pack
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Shelf Life36 months
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PubChem CID2697686
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SMILESCCOC(=O)C1=C(SC2=C1CCC2)NC(=O)CN3CCN(CC3)C(=O)C4=CC=CO4
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InChiInChI=1S/C21H25N3O5S/c1-2-28-21(27)18-14-5-3-7-16(14)30-19(18)22-17(25)13-23-8-10-24(11-9-23)20(26)15-6-4-12-29-15/h4,6,12H,2-3,5,7-11,13H2,1H3,(H,22,25)
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InChi KeyKEVHLTCEMHIJTQ-UHFFFAOYSA-N
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MSDS Available1
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Gene target
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Short nameGLX-351322
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Alternative nameGLX-351322
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