Antibody TACE (TNF-alpha converting enzyme)/ADAM17

Clone

Polyclonal
Description

The Antibody TACE (TNF-alpha converting enzyme)/ADAM17 is a α- or alpha protein sometimes glycoprotein present in blood. Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
Properties

If you buy Antibodies supplied by Kamiya they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Gene

Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
French translation

anticorps

Gene target

TACE TNF-alpha converting ADAM17
Gene symbol

TNF, TNFRSF1A, ADAM17, TNFRSF1B, LTBR
Short name

Antibody TACE (TNF-alpha converting enzyme)/ADAM17
Technique

Antibody, Enzyme, antibodies against human proteins, antibodies for, enzymes
Alternative name

(antibody to-) TACE (tumor necrosis factor-a converting enzyme)/ADAM metallopeptidase domain 17
Alternative technique

antibodies, enzymes
Alternative to gene target

ADAM metallopeptidase domain 17, ADAM18 and CD156B and CSVP and NISBD and TACE, ADAM17 and IDBG-27788 and ENSG00000151694 and 6868, PDZ domain binding, Cell surfaces, Adam17 and IDBG-130508 and ENSMUSG00000052593 and 11491, ADAM17 and IDBG-638333 and ENSBTAG00000001141 and 517541

Identity

HGNC:11916
Gene

TNFRSF1A
Long gene name

TNF receptor superfamily member 1A
Synonyms gene
- TNFR1
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
Synonyms
- TNF-R
- TNFAR
- TNFR60
- TNF-R-I
- CD120a
- TNF-R55
GenBank acession
- M75866
Locus

12p13.31
Discovery year

1991-01-15
Entrez gene record

7132
Pubmed identfication
- 1655358
- 2158863
RefSeq identity
- NM_001065
Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
VEGA ID

OTTHUMG00000168267
Locus Specific Databases
- INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations
- LRG_193

Identity

HGNC:11917
Gene

TNFRSF1B
Long gene name

TNF receptor superfamily member 1B
Synonyms gene
- TNFR2
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
Synonyms
- TNFBR
- TNFR80
- TNF-R75
- TNF-R-II
- p75
- CD120b
GenBank acession
- M32315
Locus

1p36.22
Discovery year

1991-01-15
Entrez gene record

7133
Pubmed identfication
- 2158863
- 8702885
RefSeq identity
- NM_001066
Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
VEGA ID

OTTHUMG00000001829

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data