2,7-Dichloro-dihydrofluorescein Diacetate

Alternative_name

H2DCFDA; 2',7'-dichlorofluorescin diacetate
Description

2,7-Dichloro-dihydrofluorescein diacetate is a cell-permeable, fluorescent ROS (Reactive Oxygen Species) indicator that becomes fluorescent when oxidized. 2',7'-dichlorodihydrofluorescein diacetate might be reactive toward a broad range of oxidizing reactions that may be increased during intracellular oxidant stress. This probe is widely used to monitoring cellular redox processes.
CAS Number

4091-99-0
Structure Available

Yes
Molecular Formula

C₂₄H₁₆Cl₂O₇
Molecular Weight

487.29
Cell Permeable

Yes
Purity

≥95% by HPLC
Solubilities

DMSO (>40 mg/ml)
Handling

Protect from air and light
Tag Line

A fluorescent ROS (Reactive Oxygen Species) indicator
Storage Condition

-20°C
Shipping Condition

Gel Pack
Shelf Life

36 months
MDL Number

MFCD00128955
PubChem CID

77718
PubChem CID Link
SMILES

CC(=O)OC1=C(C=C2C(C3=CC(=C(C=C3OC2=C1)OC(=O)C)Cl)C4=CC=CC=C4C(=O)O)Cl
InChi

InChI=1S/C24H16Cl2O7/c1-11(27)31-21-9-19-15(7-17(21)25)23(13-5-3-4-6-14(13)24(29)30)16-8-18(26)22(32-12(2)28)10-20(16)33-19/h3-10,23H,1-2H3,(H,29,30)
InChi Key

PXEZTIWVRVSYOK-UHFFFAOYSA-N
Data Sheet Link
MSDS Available

Yes