c-erbB2 (HER 2, neu Receptor)
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Catalog number
MBS603764
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Price
Please ask
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Size
1 mL
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Products_type
Antibody
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Products_short_name
[c-erbB2]
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Products_name_syn
[Anti -c-erbB2 (HER 2, neu Receptor)]
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Other_names
[Chain P, Single Chain Fv Of C219 Heavy Chain V101l Mutant In Complex With Synthetic Epitope Peptide]
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Clonality
Monoclonal
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Clone
[5F177]
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Specificity
Reacts with the 185kD protein in immunoblot. Recommended for Adenocarcinoma of the breast.
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Purity
Supernatant Culture supernatant
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Form
Supplied as a liquid in PBS, 1% BSA, 0.1% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20 degree C or colder. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
Western Blot (WB), Immunohistochemistry (IHC), Radioimmunoassay (RIA)
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
ERBB2
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Short name
c-erbB2 (HER 2, neu Receptor)
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Host
Mouse
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Isotype
IgG1
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Alternative name
c-v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (HER 2, neu Receptor)
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Alternative to gene target
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), CD340 and HER-2 and HER-2/neu and HER2 and MLN 19 and NEU and NGL and TKR1, ERBB2 and IDBG-46068 and ENSG00000141736 and 2064, transferase activity, nuclei, Erbb2 and IDBG-210591 and ENSMUSG00000062312 and 13866, ERBB2 and IDBG-639410 and ENSBTAG00000021798 and 505709
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Gene info
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