4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d]benzazepin-2-yl]amino]-2-methoxy-benzoic acid; Alisertib
MLN8237 is a potent and selective inhibitor of Aurora kinase A (IC₅₀ =1.2 nM). It displays >200-fold higher selectivity for Aurora kinase A over Aurora kinase B. Displays antineoplastic activity.
Is it cell-permeable?
≥98% by HPLC
Is this a salt?
Protect from air and light
Maximum time for storage
DMSO (>40 mg/ml)
For cells, cell lines and tissues in culture till half confluency.