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Picropodophyllotoxin

Picropodophyllotoxin is available 4 times from Biovision labs

2765-5 | Picropodophyllotoxin size: 5 mg | 556.68 USD

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2765-1 | Picropodophyllotoxin size: 2X1 mg | 367.3 USD

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2765-5 | Picropodophyllotoxin for cell activation size: 5 mg | 475.19 USD

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2765-1 | Picropodophyllotoxin for cell activation size: 1 mg | 162.99 USD

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Alternate Name/Synonyms (5R,5aS,8aR,9R)-5,8,8a,9-Tetrahydro­-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo[3',4':6,7­]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one; NSC 36407, PPP, Picropodophyllin
Appearance White solid
Formulation N/A
CAS Number 477-47-4
Peptide sequence N/A
Molecular Formula C₂₂H₂₂O₈
Molecular Weight 414.41
Purity ≥97% by TLC
Solubility/Reconstitution Instructions DMSO (~ 40 mg/ml)
Handling Protect from light and moisture
Tagline A potent insulin-like growth factor 1 receptor (IGF1R) inhibitor
Storage Temp. -20°C
Shipping Conditions Gel Pack
Shelf Life 36 months
MDL Number MFCD01742647
PubChem CID 72435
Category Biochemicals
Description A potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF1R) which is non-competitive with ATP. Displays no activity at IR, EGFR, FGFR or PDGFR. Inhibits IGF1R autophosphorylation IC₅₀ ~ 1 nM. Displays antiproliferative activity in numerous tumor cell lines, IC₅₀ = 0.05 - 15 mM. Exhibits antiangiogenic activitiy.
CAS number 477-47-4
Molecular weight 414.41
Other name (5R,5aS,8aR,9R)-5,8,8a,9-Tetrahydro­-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo[3',4':6,7­]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one; NSC 36407, PPP, Picropodophyllin
Molecular formula C₂₂H₂₂O₈
Physical appearance White solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Y
Purification ≥97% by TLC
Reconstitute instructions DMSO (~ 40 mg/ml)
Storage condition -20°C
Shipping condition Gel Pack
Maximum time for storage 36 months
Storage instructions Protect from light and moisture
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