ANGPTL1 Antibody (NT)
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Catalog number6761-100
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PricePlease ask
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Size100 μl
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Antibody TargetANGPTL1
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Target Alternative NameANGPTL1; ANG3; ANGPT3; ARP1; Angiopoietin-related protein 1; Angiopoietin-3; Angiopoietin-like protein 1
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Antibody TypePolyclonal
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Species ReactivitiesHuman.
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Immunogen SequenceThis ANGPTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-44 amino acids from the N-terminal region of human ANGPTL1.
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AccessionO95841
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Gene Id9068
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AppearanceColorless liquid
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FormLiquid
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Formulation100 µl of antibody in PBS with 0.09% (W/V) sodium azide
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PurificationThis antibody is purified through a protein A column, followed by peptide affinity purification.
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ApplicationWestern blot, IHC, FACS.
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Positive ControlWestern blot: HeLa cell lysate, IHC: Human placenta tissue, FACS: HeLa cells.
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Application And UsagesWestern blot: ~1:1000, IHC: ~1:50-1:100, FACS: ~1:10–1:50.
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DescriptionAngptl1 (angiopoietin-like 1), also known as angioarrestin, ARP1, ANGPT3 or previously known as angiopoietin 3 (ANG3), is a member of the angiopoietin-like family. It is highly expressed in adult tissues, particularly adrenal gland, thyroid, placenta and small intestine. Angptl1 exists as a disulfide-linked dimer and shares 45.1% identity with Ang-1 and 59% identity with Angptl2. Angptl1 consists of an N-terminus with a coiled-coil domain, potential glycosylation sites and a C-terminus with a fibrinogen-like domain. It is a secreted protein but does not function as a growth factor in endothelial cells. Angptl1 plays a distinct role in the regulation of angiogenesis; inhibiting proliferation, migration, tube formation and endothelial cell adhesion. To exert this inhibitory activity, Angptl1 is speculated to interact with a receptor on endothelial cells. In a wide variety of tumor tissues, Angptl1 expression is down-regulated suggesting that a major function of this protein involves its antiangiogenic properties.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedVerified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedVerified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolANGPTL1
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Short nameANGPTL1 Antibody (NT)
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameangiopoietin-like 1 (antibody to-) (NT)
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Alternative techniqueantibodies
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Alternative to gene targetangiopoietin-like 1, ANG3 and ANGPT3 and AngY and ARP1 and dJ595C2.2 and UNQ162, ANGPTL1 and IDBG-105082 and ENSG00000116194 and 9068, receptor binding, Extracellular, Angptl1 and IDBG-200555 and ENSMUSG00000033544 and 72713, ANGPTL1 and IDBG-636707 and ENSBTAG00000010719 and 509971
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Gene info
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Identity
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Gene
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Long gene nameangiopoietin like 1
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Synonyms gene
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Synonyms gene name
- angiopoietin-like 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-02-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibrinogen C domain containing
- Receptor ligands
- Angiopoietin like family
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
