OSTM1 Antibody, ALEXA FLUOR 555
-
Catalog number
bs-8506R-A555
-
Price
Please ask
-
Size
100ul
-
-
Long name
OSTM1 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
-
Also known as
Anti-OSTM1 PAb ALEXA FLUOR 555
-
Category
Conjugated Primary Antibodies
-
Conjugated with
ALEXA FLUOR® 555
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
OSTM1
-
Specificity
This is a highly specific antibody against OSTM1.
-
Modification
Unmodified
-
Modification Site
None
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Immunogen range
32-88/334
-
Subcellular location
Extracellular
-
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OSTM1
-
Gene ID Number
28962
-
Swiss Prot
Q86WC4
-
Tested applications
IF(IHC-P)
-
Recommended dilutions
IF(IHC-P)(1:50-200)
-
Crossreactivity
Human, Mouse, Rat
-
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigen
OSTM1 (osteopetrosis associated transmembrane protein 1), also known as gl (gray-lethal) or HSPC019, is a 338 amino acid single-pass type I membrane protein that is expressed primarily in osteoclasts and melanocytes as well as brain, kidney and spleen. Bone autosomal recessive osteopetrosis (ARO) is the most severe form of hereditary bone disease whose cellular basis is in the osteoclast and is characterized by abnormally dense bone, due to defective resorption of immature bone. ARO is suggested to be caused by mutations in the OSTM1 gene. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Defects in the OSTM1 gene are also the cause of the spontaneous gl mutant, which is responsible for a coat color defect in mice.
-
Purification
Purified by Protein A.
-
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission
553nm/568nm
-
Synonyms
GL; GIPN; OPTB5; HSPC019; Osteopetrosis-associated transmembrane protein 1; Chloride channel 7 beta subunit; OSTM1; UNQ6098/PRO21201
-
Properties
For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
Conjugation
Alexa Fluor, ALEXA FLUOR 555
-
French translation
anticorps
-
Gene target
-
Gene symbol
OSTM1-AS1, OSTM1
-
Short name
Anti-OSTM1
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Isotype
Immunoglobulin G (IgG)
-
Label
ALEXA FLUOR 555
-
Alternative name
OSTM1 Polyclonal Antibody, ALEXA FLUOR 555
-
Alternative technique
antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene name
OSTM1 antisense RNA 1
-
Synonyms gene name
- OSTM1 antisense RNA 1 (non-protein coding)
-
GenBank acession
-
Locus
-
Discovery year
2012-01-26
-
Entrez gene record
-
Classification
-
VEGA ID
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
