Mouse Monoclonal [clone MEM-43] (IgG2a) to Human CD59

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Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus

Gene target

Monoclonal MEM-43] IgG2a CD59
Gene symbol

IGLV7-43, IGHVII-43-1, SNORD115-43, IGHV3-43, IGKV1D-43, RNU6-43P, SNORD17, TARDBP, CCZ1, RLIM
Short name

Mouse Monoclonal [clone MEM-43] (IgG2a) CD59
Technique

Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
Host

mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
Isotype

IgG2a
Species

Human, Humans, Mouses
Alternative name

Mouse monoclonal [clonality MEM-43] (IgG2a) to H. sapiens CD59 molecule, complement regulatory protein
Alternative technique

murine
Alternative to gene target

CD59 molecule, complement regulatory protein, 16.3A5 and 1F5 and EJ16 and EJ30 and EL32 and G344 and HRF-20 and HRF20 and MAC-IP and MACIF and MEM43 and MIC11 and MIN1 and MIN2 and MIN3 and MIRL and MSK21 and p18-20, CD59 and IDBG-38813 and ENSG00000085063 and 966, protein binding, Extracellular, CD59 and IDBG-636427 and ENSBTAG00000002302 and 505574
Clone name

MEM-43

Identity

HGNC:5680
Gene

IGHVII-43-1
Long gene name

immunoglobulin heavy variable (II)-43-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-43-1
- immunoglobulin heavy variable (II)-43-1 pseudogene
Synonyms
- IGHV(II)-43-1
GenBank acession
- AB019438
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28367
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000191837

Identity

HGNC:11571
Gene

TARDBP
Long gene name

TAR DNA binding protein
Synonyms
- TDP-43
- ALS10
GenBank acession
- U23731
Locus

1p36.22
Discovery year

2000-01-28
Entrez gene record

23435
Pubmed identfication
- 7745706
- 31039256
RefSeq identity
- NM_007375
Classification
- RNA binding motif containing
VEGA ID

OTTHUMG00000002120
Locus Specific Databases
- ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database
- LRG_659

Identity

HGNC:21691
Gene

CCZ1
Long gene name

CCZ1 homolog, vacuolar protein trafficking and biogenesis associated
Synonyms gene
- C7orf28A
Synonyms gene name
- chromosome 7 open reading frame 28A
- CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
Synonyms
- CGI-43
- CCZ1A
GenBank acession
- AF151801
Locus

7p22.1
Discovery year

2003-07-14
Entrez gene record

51622
Pubmed identfication
- 10810093
- 20305638
RefSeq identity
- NM_015622
VEGA ID

OTTHUMG00000155502