Macrophage Colony stimulating factor 1 Antibody / Csf1

• Catalog number
  R31901
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Macrophage Colony stimulating factor 1 / Csf1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  IHC-P, ELISA
• Recommended dilutions
  IHC (Paraffin): 0.5-1ug/ml,ELISA : 0.1-0.5ug/ml
• Notes
  Optimal dilution of the Csf-1 antibody should be determined by the researcher.
• Intented use
  This Csf-1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P07141
• Purity
  Antigen affinity
• Description
  Macrophage Colony Stimulating Factor 1, also called MCSF or CSF1, is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival ofmonocytes, macrophages, and bone marrow progenitor cells. MCSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of MCSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or MCSFR encoded by the c-fms proto-oncogene), MCSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
• Immunogen
  Amino acids 33-262 of mouse Colony stimulating factor 1 were used as the immunogen for the Csf-1 antibody.
• Storage
  After reconstitution, the Csf-1 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Cytoplasmic, membrane
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Additional description
  Colonies can be formed by stimulating factors or recombinant GM-CSF and CSFs activity expressed in Units compared to a standard. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
• French translation
  anticorps

• Gene target
  Macrophage   Colony   stimulating   factor   Csf1  
• Gene symbol
  CSF1
• Short name
  Anti-Macrophage Colony stimulating factor 1 / Csf1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Macrophage Colony stimulating factor 1 / Csf1
• Alternative technique
  antibodies
• Alternative to gene target
  colony stimulating factor 1 (macrophage), CSF-1 and MCSF, CSF1 and IDBG-100920 and ENSG00000184371 and 1435, protein homodimerization activity, Extracellular, Csf1 and IDBG-185535 and ENSMUSG00000014599 and 12977, CSF1 and IDBG-635251 and ENSBTAG00000000283 and 281094

Gene info

• Identity
  HGNC:2432
• Gene
  CSF1
• Long gene name
  colony stimulating factor 1
• Synonyms gene name
  • colony stimulating factor 1 (macrophage)
• Synonyms
  • M-CSF
  • MCSF
  • MGC31930
• Synonyms name
  • macrophage colony stimulating factor 1
• GenBank acession
  • BC021117
• Locus
  1p13.3
• Discovery year
  1986-01-01
• Entrez gene record
  1435
• Pubmed identfication
  • 1540160
• RefSeq identity
  • NM_000757
• VEGA ID
  OTTHUMG00000011646

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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