CNOT3 (KIAA0691, LENG2, NOT3, CCR4-NOT Transcription Complex Subunit 3, CCR4-associated Factor 3, Leukocyte Receptor Cluster Member 2) Antibody

• Catalog number
  GEN648321
• Price
  Please ask
• Size
  100ug

• Also known as
  CNOT3
• Other names
  CCR4-NOT transcription complex subunit 3; CCR4-NOT transcription complex subunit 3; CCR4-NOT transcription complex subunit 3; CCR4-associated factor 3; leukocyte receptor cluster member 2; NOT3 (negative regulator of transcription 3, yeast) homolog; CCR4-NOT transcription complex, subunit 3; CCR4-associated factor 3; Leukocyte receptor cluster member 2
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  CNOT3; CNOT3; NOT3; LENG2; NOT3H; KIAA0691; LENG2; NOT3
• Gene name synonims
  CNOT3; CNOT3; NOT3; LENG2; NOT3H; KIAA0691; LENG2; NOT3
• Other gene names
  CNOT3; CNOT3; NOT3; LENG2; NOT3H; KIAA0691; LENG2; NOT3
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1,k
• Clone
  4B8
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes human CNOT3.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein A affinity chromatography.
• Form Appearance
  Supplied as a liquid in PBS, pH 7.2.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested applications
  ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
• French translation
  anticorps

• Gene target
  CNOT3   KIAA0691   LENG2   NOT3   CCR4-NOT   Transcription   Complex   Subunit   CCR4-associated   Factor   Leukocyte   Receptor   Cluster   Member  
• Gene symbol
  CNOT3, CNOT6, CCR4, RNA28S1, DUX1, DUX3, DUX5, TAS2R36
• Short name
  CNOT3 (KIAA0691, LENG2, NOT3, CCR4-NOT Transcription Complex Subunit 3, CCR4-associated Factor 3, Leukocyte Receptor Cluster Member 2) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Anti-CNOT3 (KIAA0691, LENG2, NOT3, CCR4-NOT Transcription Complex Subunit 3, CCR4-associated Factor 3, Leukocyte Receptor Cluster Member 2)
• Alternative technique
  antibodies
• Alternative to gene target
  chemokine (C-C motif) receptor 4, CC-CKR-4 and CD194 and ChemR13 and CKR4 and CMKBR4 and HGCN:14099 and K5-5, CCR4 and IDBG-23908 and ENSG00000183813 and 1233, C-C chemokine receptor activity, Cell surfaces, Ccr4 and IDBG-203512 and ENSMUSG00000047898 and 12773, CCR4 and IDBG-644121 and ENSBTAG00000034883 and 100851774,408019

Gene info

• Identity
  HGNC:7879
• Gene
  CNOT3
• Long gene name
  CCR4-NOT transcription complex subunit 3
• Synonyms gene
  • NOT3
• Synonyms gene name
  • CCR4-NOT transcription complex, subunit 3
• Synonyms
  • NOT3H
  • KIAA0691
  • LENG2
• Synonyms name
  • NOT3 (negative regulator of transcription 3, yeast) homolog
• GenBank acession
  • AF180474
• Locus
  19q13.42
• Discovery year
  1996-07-19
• Entrez gene record
  4849
• Pubmed identfication
  • 10637334
  • 9734811
• RefSeq identity
  • NM_014516
• Classification
  • CCR4-NOT transcription complex
• VEGA ID
  OTTHUMG00000066468

Gene info

• Identity
  HGNC:14099
• Gene
  CNOT6
• Long gene name
  CCR4-NOT transcription complex subunit 6
• Synonyms gene name
  • CCR4-NOT transcription complex, subunit 6
• Synonyms
  • CCR4
  • KIAA1194
  • Ccr4a
• GenBank acession
  • AB033020
• Locus
  5q35.3
• Discovery year
  2001-03-30
• Entrez gene record
  57472
• Pubmed identfication
  • 11889047
• RefSeq identity
  • NM_015455
• Classification
  • CCR4-NOT transcription complex
• VEGA ID
  OTTHUMG00000130935

Gene info

• Identity
  HGNC:1605
• Gene
  CCR4
• Long gene name
  C-C motif chemokine receptor 4
• Synonyms gene name
  • chemokine (C-C motif) receptor 4
• Synonyms
  • CC-CKR-4
  • CMKBR4
  • CKR4
  • k5-5
  • ChemR13
  • CD194
• GenBank acession
  • X85740
• Locus
  3p22.3
• Discovery year
  1996-05-15
• Entrez gene record
  1233
• Pubmed identfication
  • 7642634
  • 8884276
• Classification
  • C-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000130752

Gene info

• Identity
  HGNC:44286
• Gene
  RNA28S1
• Long gene name
  RNA, 28S ribosomal 1
• Synonyms name
  • 28S rRNA 1
• Locus
  13p12 not on reference assembly
• Discovery year
  2012-08-07
• Entrez gene record
  106632267
• Classification
  • 28S ribosomal RNAs

Gene info

• Identity
  HGNC:3079
• Gene
  DUX1
• Long gene name
  double homeobox 1
• Synonyms gene name
  • double homeobox, 1
• GenBank acession
  • AJ001481
• Locus
  not on reference assembly
• Discovery year
  1999-12-01
• Entrez gene record
  26584
• Pubmed identfication
  • 9736770
  • 11245978
• RefSeq identity
  • NM_012146

Gene info

• Identity
  HGNC:3081
• Gene
  DUX3
• Long gene name
  double homeobox 3
• GenBank acession
  • AF133130
• Locus
  not on reference assembly
• Discovery year
  1999-12-01
• Entrez gene record
  26582
• Pubmed identfication
  • 11245978
• RefSeq identity
  • NM_012148

Gene info

• Identity
  HGNC:3083
• Gene
  DUX5
• Long gene name
  double homeobox 5
• GenBank acession
  • AF133131
• Locus
  not on reference assembly
• Discovery year
  1999-12-01
• Entrez gene record
  26581
• Pubmed identfication
  • 11245978
• RefSeq identity
  • NM_012149

Gene info

• Identity
  HGNC:19115
• Gene
  TAS2R36
• Long gene name
  taste 2 receptor member 36
• Synonyms gene name
  • taste receptor, type 2, member 36
• Synonyms
  • T2R36
• GenBank acession
  • AX097755
• Locus
  12 not on reference assembly
• Discovery year
  2002-09-26
• Entrez gene record
  266666
• Classification
  • Taste 2 receptors

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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