Mouse anti EGFR
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Catalog numberX1568M
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PricePlease ask
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Size100 μg
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CategoryPrimary Antibodies
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Long descriptionEGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor- (TGF- ), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
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Antibody come fromUnique peptide sequence derived from the D1 blade of the G 5 protein.
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Other descriptionProvided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
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CloneH11
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Antigen antibody binding interactionMouse anti EGFR Antibody
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Antibody is raised inMouse
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Antibody s reacts withHuman doens not react with mouse and rat. Others not known.
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Antibody s reacts with these speciesThis antibody doesn't cross react with other species
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Antibody s specificityNo Data Available
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ApplicationWB of Extracellular domain, FC, IF, IP (native only), IHC (Paraffin)
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Antibody s suited forAntibody can be used for Western blotting (5-10 µg/ml). Optimal concentration should be evaluated by serial dilutions.
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Storage-20ºC
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Relevant references1. Liang, J.J., et al. 'RGS7 complex formation and colocalization with the Gbeta5 subunit in the adult rat and influence on Gbeta5gamma2-mediated PLCbeta signaling.' J. Neurosci. Res. 2000: 60, 58-64_x000B__x000B_2. Cabrera, J.L., et al. 'Identification of the Gbeta5-RGS7 protein complex in the retina.' Biochem Biophys Res Commun. 1998: 249, 898-902_x000B__x000B_3. Watson, A.J., et al. 'A novel form of the G protein beta subunit Gbeta5 is specifically expressed in the vertebrate retina.' J. Biol. Chem. 1996: 271, 28154-28160
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Protein numbersee ncbi
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WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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Gene target
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Gene symbolEGFR-AS1, EGILA, EGFR, RHBDF1
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Short nameMouse anti EGFR
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TechniqueMouse, anti, antibody to, mouses
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Hostmouse
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IsotypeIgG1
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Labelunlabeled
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SpeciesMouse, Mouses
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Alternative nameMouse antibody to epidermal growth factor receptor
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Alternative techniquemurine, antibodies
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Alternative to gene targetepidermal growth factor receptor, ERBB and ERBB1 and HER1 and mENA and PIG61, EGFR and IDBG-16933 and ENSG00000146648 and 1956, transferase activity, nuclei, Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649, EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217
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Gene info
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Identity
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Gene
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Long gene nameEGFR antisense RNA 1
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Locus
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Discovery year2012-11-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameEGFR interacting lncRNA
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Synonyms
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Locus
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Discovery year2019-09-27
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Pubmed identfication
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Classification
- Long non-coding RNAs with non-systematic symbols
Gene info
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Identity
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Gene
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Long gene nameepidermal growth factor receptor
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Synonyms gene
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Synonyms gene name
- epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
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Synonyms
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Synonyms name
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Erb-b2 receptor tyrosine kinases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namerhomboid 5 homolog 1
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Synonyms gene
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Synonyms gene name
- chromosome 16 open reading frame 8
- rhomboid family 1 (Drosophila)
- rhomboid 5 homolog 1 (Drosophila)
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-04-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Rhomboid family
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data