Tumor Necrosis Factor Receptor 1, p55/p60 (TNFR 1, TNFR1, Tnfr-1, TNF-R1, TNF-R, Tumor Necrosis Factor Receptor Type I, TNFRI, TNFR-I, TNF-RI, TNF-R-I, CD120a, FPF, p55, p55-R, p60, TNF-R55, TNFRp55, TNFR60, Tumor Necrosis Factor alpha Receptor, TNFAR, TN[Tumor Necrosis Factor Receptor 1, p55/p60]
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Catalog numberMBS631917
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PricePlease ask
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SizeNA
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Products_typeAntibody
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ReactivityMouse
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DescriptionThe Tumor Necrosis Factor Receptor 1, p55/p60 (TNFR 1, TNFR1, Tnfr-1, TNF-R1, TNF-R, Tumor Necrosis Factor Receptor I, TNFRI, TNFR-I, TNF-RI, TNF-R-I, CD120a, FPF, p55, p55-R, p60, TNF-R55, TNFRp55, TNFR60, Tumor Necrosis Factor alpha Receptor, TNFAR, TN[Tumor Necrosis Factor Receptor 1, p55/p60] is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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GeneTumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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Gene target
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Gene symbolTNFRSF1A, TNF, LTBR, TNFRSF1B, FPR3, FABP6, RRAS, DAD1P1, HNRNPR, CLDN4
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Short nameTumor Necrosis Factor Receptor 1, p55/p60 (TNFR 1, TNFR1, Tnfr-1, TNF-R1, TNF-R, Tumor Necrosis Factor Receptor I, TNFRI, TNFR-I, TNF-RI, TNF-R-I, CD120a, FPF, p55, p55-R, p60, TNF-R55, TNFRp55, TNFR60, Tumor Necrosis Factor alpha Receptor, TNFAR, TN[Tumor Necrosis Factor Receptor 1, p55/p60]
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HostRat
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Alternative nameTumor Necrosis Factor Receptor 1, p55/p60 (TNFR 1, TNFR1, Tnfr-1, tumor necrosis factor-R1, tumor necrosis factor-R, Tumor Necrosis Factor Receptor classification I, TNFRI, TNFR-I, tumor necrosis factor-RI, tumor necrosis factor-R-I, CD120a, FPF, p55, p55-R, p60, tumor necrosis factor-R55, TNFRp55, TNFR60, Tumor Necrosis Factor a Receptor, TNFAR, TN[Tumor Necrosis Factor Receptor 1, p55/p60]
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Alternative to gene targettumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943
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Tissuetumor
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Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1A
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nametumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelymphotoxin beta receptor
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-03-12
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1B
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameformyl peptide receptor 3
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Synonyms gene
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Synonyms gene name
- formyl peptide receptor-like 2
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Synonyms
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Locus
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Discovery year1991-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Formyl peptide receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namefatty acid binding protein 6
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Synonyms gene name
- fatty acid binding protein 6, ileal
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-09-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fatty acid binding protein family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRAS related
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Synonyms gene name
- related RAS viral (r-ras) oncogene homolog
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Synonyms
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Synonyms name
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RAS type GTPase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedefender against cell death 1 pseudogene 1
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Synonyms gene
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Synonyms gene name
- defender against cell death 1-like
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Synonyms
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Locus
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Discovery year2007-07-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
Gene info
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Identity
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Gene
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Long gene nameheterogeneous nuclear ribonucleoprotein R
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-06-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Heterogeneous nuclear ribonucleoproteins
- RNA binding motif containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameclaudin 4
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-04-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Claudins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
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Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data