NFkB p65, phosphorylated (Ser536) (NF-kB, Nuclear Factor kappa B, MGC131774, NFKB3, Nuclear Factor NF-Kappa-B p65, Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B Cells, RelA, Transcription Factor p65, v-Rel Avian Reticuloendotheliosis Viral

  • Catalog number
    MBS624297
  • Price
    Please ask
  • Size
    5x0.05 mg
  • Products_type
    Antibody
  • Products_short_name
    [NFkB p65]
  • Products_name_syn
    [Anti -NFkB p65, phosphorylated (Ser536) (NF-kB, Nuclear Factor kappa B, MGC131774, NFKB3, Nuclear Factor NF-Kappa-B p65, Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B Cells, RelA, Transcription Factor p65, v-Rel Avian Reticuloendotheliosis Viral]
  • Other_names
    [NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform c; NF-kappa-B inhibitor-interacting Ras-like protein 2; NF-kappa-B inhibitor-interacting Ras-like protein 2; kappa B-Ras protein 2; I-kappa-B-interacting Ras-like protein 2; NFKB inhibitor interacting Ras-like protein 2; NFKB inhibitor interacting Ras-like 2; I-kappa-B-interacting Ras-like protein 2]
  • Other_gene_names
    [NKIRAS2; NKIRAS2; KBRAS2; kappaB-Ras2; KBRAS2; Kappa B-Ras protein 2; KappaB-Ras2]
  • Clonality
    Polyclonal
  • Reactivity
    Human
  • Specificity
    Recognizes human NFkB p65 when phosphorylated at Ser536. Species sequence homology: mouse and rat.
  • Purity
    Affinity Purified Purified by immunoaffinity chromatography.
  • Form
    Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
  • Storage_stability
    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
  • Tested_application
    ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
  • Description
    Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
  • Gene
    NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
  • Gene target
  • Gene symbol
    NFE4, NFE2, NEFH, NFKB1, INA, NFASC, NFATC1, NFYC, NFATC2, NFIL3
  • Short name
    NFkB p65, phosphorylated (Ser536) (NF-kB, Factor kappa B, MGC131774, NFKB3, Factor NF-Kappa-B p65, Factor Of Kappa Light Polypeptide Enhancer In B Cells, RelA, Transcription Factor p65, v-Rel Avian Reticuloendotheliosis
  • Technique
    light
  • Host
    Rabbit
  • Isotype
    IgG
  • Alternative name
    NFkB p65, phosphorylated (Ser536) (NF-kB, Nuclear Factor kappa B, MGC131774, NFKB3, Nuclear Factor NF-Kappa-B p65, Nuclear Factor on Kappa Light multipeptide Gene Enhancer In B Cells, v-v-rel reticuloendotheliosis viral oncogene homolog (avian) reticuloendotheliosis viral oncogene homolog A (avian), Transcription Factor p65, v-v-rel reticuloendotheliosis viral oncogene homolog (avian) Avian Reticuloendotheliosis Viral
  • Alternative to gene target
    v-rel reticuloendotheliosis viral oncogene homolog (avian), C-Rel, REL and IDBG-53133 and ENSG00000162924 and 5966, sequence-specific DNA binding, nuclei, Rel and IDBG-155648 and ENSMUSG00000020275 and 19696, REL and IDBG-634277 and ENSBTAG00000015386 and 509135
  • Tissue
    cells
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    nuclear factor, erythroid 2
  • Synonyms gene name
    • nuclear factor (erythroid-derived 2), 45kD
    • nuclear factor (erythroid-derived 2), 45kDa
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1993-11-03
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Basic leucine zipper proteins
  • VEGA ID
Gene info
Gene info
Gene info
  • Identity
  • Gene
    INA
  • Long gene name
    internexin neuronal intermediate filament protein alpha
  • Synonyms gene
  • Synonyms gene name
    • internexin neuronal intermediate filament protein, alpha
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1999-03-24
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Intermediate filaments Type IV
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    nuclear factor of activated T cells 1
  • Synonyms gene name
    • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
    • nuclear factor of activated T-cells 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1994-11-16
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Nuclear factors of activated T-cells
    • IPT domain containing
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    nuclear factor of activated T cells 2
  • Synonyms gene name
    • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
    • nuclear factor of activated T-cells 2
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1994-11-16
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • IPT domain containing
    • Nuclear factors of activated T-cells
    • MicroRNA protein coding host genes
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Process of growing viruses in live animals, plants, or cultured cells.
  • Tree numbers
    • E01.370.225.875.970
    • E05.200.875.970
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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