NGFR Antibody (Clone # 8G3G10)
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Catalog number
6789-100
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Price
Please ask
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Size
100 μl
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Antibody Target
NGFR
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Target Alternative Name
CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; NGFR
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Antibody Type
Monoclonal
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Clone
Clone # 8G3G10
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Species Reactivities
Human.
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Immunogen Sequence
This NGFR antibody is generated from mouse immunized with NGFR recombinant protein.
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Accession
P08138
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Gene Id
4804
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Appearance
Colorless liquid
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Form
Liquid
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Formulation
This antibody is purified through a protein G column, followed by dialysis against PBS.
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Application
Western blot, IF, FACS.
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Positive Control
Western blot: mouse heart tissue lysate, IF: SY5Y cells, FACS: human brain tissue.
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Application And Usages
WB: 1:500 – 1:2000, IHC: 1:50 – 1:100, IF: 1:100.
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Description
NGFR, a 75 kd glycoprotein (also known as P-75NTR), is the first of neurotrophin receptors to be isolated and is a member of the tumor necrosis factor (TNF) receptor family. It is expressed not only in sympathetic and sensory neurons, but also in various neural crest cell or tumor derivatives such as melanocytes, melanomas, neuroblastomas, pheochromocytomas, neurofibromas, and neurotized nevi (type C melanocytes). NGFR has been shown to be a reliable marker for desmoplastic and neurotropic melanoma by several groups. It is now apparent that expression of NGFR is ubiquitous and not limited to the nervous system, being expressed in mature nonneural cells such as perivascular cells, follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells and myoepithelial cells. Studies in prostate and urothelial cancer suggest that NGFR may act as a tumour suppressor, negatively regulating cell growth and proliferation. Anti-NGFR labels the myoepithelial cells of breast ducts and intralobular fibroblasts of breast ducts and thus aides in the diagnosis of malignancy in the breast.
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Storage Condition
-20 °C
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Shipping Condition
gel pack
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Shelf Life
12 months
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Usage
For Research Use Only! Not to be used in humans.
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Handling
The antibody solution should be gently mixed before use.
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Western Blot Verified
Verified
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Immunocytochemistry Verified
Verified
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Immunofluorescence Verified
Verified
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Immunoprecipitation Verified
Not Verified
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ELISA Verified
Not Verified
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ChIP Verified
Not Verified
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Flow Cytometry Verified
Not Verified
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Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
NGFR-AS1, NGFR
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Short name
NGFR Antibody (Clone # 8G3G10)
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Mouse IgG1
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Alternative name
nerve growth factor receptor (antibody to-) (clonality # 8G3G10)
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Alternative technique
antibodies
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Alternative to gene target
nerve growth factor receptor, CD271 and Gp80-LNGFR and p75(NTR) and p75NTR and TNFRSF16, NGFR and IDBG-57653 and ENSG00000064300 and 4804, nerve growth factor binding, nuclei, Ngfr and IDBG-209608 and ENSMUSG00000000120 and 18053, NGFR and IDBG-638806 and ENSBTAG00000020979 and 353110
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Gene info
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Identity
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Gene
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Long gene name
NGFR antisense RNA 1
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Locus
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Discovery year
2021-04-07
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Entrez gene record
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RefSeq identity
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Classification
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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