Hypoxia Inducible Factor 1 alpha (Hypoxia Inducible Factor 1 alpha Subunit Basic Helix-loop-helix Transcription Factor, HIF1A, HIF-1 alpha, HIF-1A, HIF1-alpha, ARNT Interacting Protein, Basic Helix-loop-helix PAS Protein MOP1, Member of PAS Protein 1, Mem Antibody
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Catalog numberGEN606672
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PricePlease ask
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Size100ul
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Also known asHypoxia Inducible Factor 1 alpha
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Other nameshypoxia-inducible factor 1-alpha isoform 1; Hypoxia-inducible factor 1-alpha; hypoxia-inducible factor 1-alpha; HIF-1-alpha; OTTHUMP00000179061; OTTHUMP00000179062; OTTHUMP00000179063; member of PAS protein 1; ARNT interacting protein; ARNT-interacting protein; member of PAS superfamily 1; PAS domain-containing protein 8; basic-helix-loop-helix-PAS protein MOP1; class E basic helix-loop-helix protein 78; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameHIF1A; HIF1A; HIF1; MOP1; PASD8; bHLHe78; HIF-1alpha; HIF1-ALPHA; BHLHE78; MOP1; PASD8
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Gene name synonimsHIF1A; HIF1A; HIF1; MOP1; PASD8; bHLHe78; HIF-1alpha; HIF1-ALPHA; BHLHE78; MOP1; PASD8
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Other gene namesHIF1A; HIF1A; HIF1; MOP1; PASD8; bHLHe78; HIF-1alpha; HIF1-ALPHA; BHLHE78; MOP1; PASD8
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG
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Clone9G81
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Host organismMouse (Mus musculus)
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Source organismHuman (Homo sapiens)
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Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes human HIF-1 alpha at ~120kD. Multiple bands may be observed at ~120kD representing post-translational modications.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodAffinity Purified by Protein G affinity chromatography.
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Form AppearanceSupplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
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ConcentrationN/A
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Storage and shippingStore the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested applicationsWestern Blot (WB)
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DescriptionThe Hypoxia Factor 1 alpha (Hypoxia Factor 1 alpha Subunit Helix-loop-helix Transcription Factor, HIF1A, HIF-1 alpha, HIF-1A, HIF1-alpha, ARNT Interacting Protein, Helix-loop-helix PAS Protein MOP1, Member of PAS Protein 1, Mem Antibody is a α- or alpha protein sometimes glycoprotein present in blood. Basic proteins pH>7 are often produced recombinant and shouldn’t be precipitated by formic acid buffer. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolHIF1A, ARNT, HIF1A-AS1, HIF1A-AS2, HIF1A-AS3, SETD2, NPAS4, IGKV2OR2-1, POU2F3, IGHD1OR15-1A
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Short nameHypoxia Factor 1 alpha (Hypoxia Factor 1 alpha Subunit Helix-loop-helix Transcription Factor, HIF1A, HIF-1 alpha, HIF-1A, HIF1-alpha, ARNT Interacting Protein, Helix-loop-helix PAS Protein MOP1, Member of PAS Protein 1, Mem Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameAnti-Hypoxia Inducible Factor 1 alpha (Hypoxia Inducible Factor 1 alpha Subunit Basic Helix-loop-helix Transcription Factor, HIF1A, HIF-1 alpha, HIF-1A, HIF1-alpha, ARNT Interacting Protein, Basic Helix-loop-helix PAS Protein MOP1, Member of PAS Protein 1, Mem
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Alternative techniqueantibodies
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Alternative to gene targethypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), bHLHe78 and HIF-1A and HIF-1alpha and HIF1 and HIF1-ALPHA and MOP1 and PASD8, HIF1A and IDBG-8510 and ENSG00000100644 and 3091, Hsp90 protein binding, nuclei, Hif1a and IDBG-148620 and ENSMUSG00000021109 and 15251, HIF1A and IDBG-646757 and ENSBTAG00000020935 and 281814
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Gene info
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Identity
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Gene
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Long gene namehypoxia inducible factor 1 subunit alpha
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Synonyms gene name
- hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-03-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Basic helix-loop-helix proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namearyl hydrocarbon receptor nuclear translocator
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Synonyms
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GenBank acession
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Locus
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Discovery year1990-01-22
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Entrez gene record
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Classification
- Basic helix-loop-helix proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameHIF1A antisense RNA 1
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Synonyms gene name
- HIF1A antisense RNA 1 (non-protein coding)
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Synonyms
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GenBank acession
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Locus
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Discovery year2011-09-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameHIF1A antisense RNA 2
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Synonyms gene name
- HIF1A antisense RNA 2 (non-protein coding)
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Synonyms
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Locus
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Discovery year2011-09-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameHIF1A antisense RNA 3
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Locus
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Discovery year2019-05-01
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Entrez gene record
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RefSeq identity
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene nameSET domain containing 2, histone lysine methyltransferase
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Synonyms gene name
- SET domain containing 2
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SET domain containing
- Lysine methyltransferases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameneuronal PAS domain protein 4
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-09-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Basic helix-loop-helix proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 2/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 2/OR2-1
- immunoglobulin kappa variable 2/OR2-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namePOU class 2 homeobox 3
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Synonyms gene name
- POU domain class 2, transcription factor 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-11-28
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Entrez gene record
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Pubmed identfication
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Classification
- POU class homeoboxes and pseudogenes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy diversity 1/OR15-1A (non-functional)
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Synonyms gene name
- immunoglobulin heavy diversity 1/OR15-1A
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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Classification
- Immunoglobulin heavy (IGH) orphons
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data