IL-22, human recombinant

• Catalog number
  4601-1000
• Price
  Please ask
• Size
  1 mg

• Synonyms
  IL-TIF, TIFa, IL-10-related T-cell-derived-inducible factor, IL-22, ILTIF, IL-D110, zcyto18, MGC79382, MGC79384, TIFIL-23
• Alternative_names
  IL-TIF, TIFa, IL-10-related T-cell-derived-inducible factor, IL-22, ILTIF, IL-D110, zcyto18, MGC79382, MGC79384, TIFIL-23
• Description
  A potent mediator of cellular inflammatory responses
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥97%
• Assay
  SDS-PAGE
• Purity
  ≥97%
• Biological activity
  Recombinant IL-22 activates STAT following receptor-ligand interaction.
• Molecular Weight
  16.8 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized protein
• Physical form description
  Lyophilized from 1 mM Sodium Citrate, pH 4.0.
• Reconstitution Instructions
  Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum. This solution can then be stored at 4°C for 1 week or -20° for future use.
• Background Information
  Human Interleukin-22 (IL-22), also known as T cell-derived inducible factor (ILTIF), is a cytokine that is structurally related to IL-10. Studies have shown that IL-22 induces acute-phase reactants in vitro and in vivo, suggesting that the cytokine contributes to the regulation of inflammatory responses. Recombinant human IL-22 is a 16.8 kDa protein consisting of 147 amino acids residues.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  IL-22  
• Gene symbol
  IL22, SNORD114-22, PIRC112, PIRC111, PIRC108, PIRC109, VN1R112P, PIRC107, PIRC110, PIRC106
• Short name
  IL-22, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Interleukin-22, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:14900
• Gene
  IL22
• Long gene name
  interleukin 22
• Synonyms
  • ILTIF
  • IL-21
  • zcyto18
  • IL-TIF
  • IL-D110
  • TIFa
  • TIFIL-23
  • IL-22
  • MGC79382
  • MGC79384
• Synonyms name
  • IL-10-related T-cell-derived inducible factor
• GenBank acession
  • AF279437
• Locus
  12q15
• Discovery year
  2001-03-12
• Entrez gene record
  50616
• Pubmed identfication
  • 10954742
  • 10875937
• RefSeq identity
  • NM_020525
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000169119
• Locus Specific Databases
  • LRG_1248

Gene info

• Identity
  HGNC:33010
• Gene
  SNORD114-22
• Long gene name
  small nucleolar RNA, C/D box 114-22
• Synonyms
  • 14q(II-22)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767600
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003215.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:37616
• Gene
  PIRC112
• Long gene name
  piwi-interacting RNA cluster 112
• Locus
  22
• Discovery year
  2009-11-05
• Entrez gene record
  100313803
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37615
• Gene
  PIRC111
• Long gene name
  piwi-interacting RNA cluster 111
• Locus
  22
• Discovery year
  2009-11-05
• Entrez gene record
  100313937
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37612
• Gene
  PIRC108
• Long gene name
  piwi-interacting RNA cluster 108
• Locus
  22
• Discovery year
  2009-11-05
• Entrez gene record
  100313878
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37613
• Gene
  PIRC109
• Long gene name
  piwi-interacting RNA cluster 109
• Locus
  22
• Discovery year
  2009-11-05
• Entrez gene record
  100313913
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37437
• Gene
  VN1R112P
• Long gene name
  vomeronasal 1 receptor 112 pseudogene
• Locus
  22
• Discovery year
  2009-10-06
• Entrez gene record
  100312854
• RefSeq identity
  • NG_015712
• Classification
  • Vomeronasal receptors

Gene info

• Identity
  HGNC:37611
• Gene
  PIRC107
• Long gene name
  piwi-interacting RNA cluster 107
• Locus
  22
• Discovery year
  2009-11-05
• Entrez gene record
  100313802
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37614
• Gene
  PIRC110
• Long gene name
  piwi-interacting RNA cluster 110
• Locus
  22
• Discovery year
  2009-11-05
• Entrez gene record
  100313879
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37610
• Gene
  PIRC106
• Long gene name
  piwi-interacting RNA cluster 106
• Locus
  22
• Discovery year
  2009-11-05
• Entrez gene record
  100313877
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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