Human CellExp™ VAPB, Human recombinant
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Catalog number
P1135-10
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Price
Please ask
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Size
10 ug
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Synonyms
VAPB, ALS8, VAMP-B, Vesicle-associated membrane protein-associated protein B/C
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Alternative_names
VAPB, ALS8, VAMP-B, Vesicle-associated membrane protein-associated protein B/C
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Description
Protein involved in cellular calcium homeostasis regulation
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Recombinant
Yes
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Source
HEK 293 cells
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Purity by SDS PAGE
> 95%
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Assay
SDS-PAGE
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Endotoxin Level
< 1.0 EU per/ug
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Molecular Weight
15.8 kDa
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Storage Temp
-20°C
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Shipping
Gel Pack
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Shelf Life
12 months
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Appearance
Lyophilized
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Physical form description
Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.
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Reconstitution Instructions
Reconstitute in sterile deionized water to the desired protein concentration.
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Background Information
Vesicle-associated membrane protein-associated protein B/C (VAPB) is also known as VAMP-associated protein B/C (VAMP-B/VAMP-C or VAP-B/VAP-C), which is a single-pass type IV membrane protein and belongs to the VAMP-associated protein ( VAP ) family. Involved in cellular calcium homeostasis regulation, VAPB participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity as well. VAPB can interact with VAMP1, VAMP2, HCV NS5A, NS5B, ZFYVE27 (via MSP domain) and RMDN3. Human VAPB is involved in hepatitis C virus replication through interaction with NS5A and NS5B.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
VAPB
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Short name
CellExp™ VAPB, recombinant
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Humans
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Alternative name
H. sapiens CellExp™ VAPB, H. sapiens Rec.
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Alternative technique
rec
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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