CDKN2A, CT (Cyclin-dependent Kinase Inhibitor 2A, Isoforms 1/2/3, Cyclin-dependent Kinase 4 Inhibitor A, CDK4I, Multiple Tumor Suppressor 1, MTS-1, p16-INK4a, p16-INK4, p16INK4A, CDKN2, MTS1) Antibody

• Catalog number
  GEN642191
• Price
  Please ask
• Size
  100ul

• Also known as
  CDKN2A
• Other names
  cyclin-dependent kinase inhibitor 2A isoform p12; Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3; cyclin-dependent kinase inhibitor 2A; CDK4 inhibitor p16-INK4; multiple tumor suppressor 1; cell cycle negative regulator beta; cyclin-dependent kinase 4 inhibitor A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A; Cyclin-dependent kinase 4 inhibitor A; CDK4I; Multiple tumor suppressor 1; MTS-1; p16-INK4a
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  CDKN2A; CDKN2A; ARF; MLM; P14; P16; P19; CMM2; INK4; MTS1; TP16; CDK4I; CDKN2; INK4A; MTS-1; P14ARF; P19ARF; P16INK4; P16INK4A; P16-INK4A; CDKN2; MTS1; CDK4I; MTS-1; p16-INK4; p16INK4A
• Gene name synonims
  CDKN2A; CDKN2A; ARF; MLM; P14; P16; P19; CMM2; INK4; MTS1; TP16; CDK4I; CDKN2; INK4A; MTS-1; P14ARF; P19ARF; P16INK4; P16INK4A; P16-INK4A; CDKN2; MTS1; CDK4I; MTS-1; p16-INK4; p16INK4A
• Other gene names
  CDKN2A; CDKN2A; ARF; MLM; P14; P16; P19; CMM2; INK4; MTS1; TP16; CDK4I; CDKN2; INK4A; MTS-1; P14ARF; P19ARF; P16INK4; P16INK4A; P16-INK4A; CDKN2; MTS1; CDK4I; MTS-1; p16-INK4; p16INK4A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  13B163
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Human; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Ascites
• Form Appearance
  Ascites fluid containing 0.03% sodium azide.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested applications
  ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
• French translation
  anticorps

• Gene target
  CDKN2A   Cyclin-dependent   Kinase   Inhibitor   Isoforms   1/2/3   Cyclin-dependent   Kinase   Inhibitor   CDK4I   Multiple   Tumor   Suppressor   MTS-1   p16-INK4a   p16-INK4   p16INK4A   CDKN2   MTS1  
• Gene symbol
  CDKN2A, S100A4, CDKN2A-DT, TIMM8A, CDKN2B, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1
• Short name
  CDKN2A, CT (Cyclin-dependent Kinase Inhibitor 2A, Isoforms 1/2/3, Cyclin-dependent Kinase 4 Inhibitor A, CDK4I, Multiple Tumor Suppressor 1, MTS-1, p16-INK4a, p16-INK4, p16INK4A, CDKN2, MTS1) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Anti-CDKN2A, CT (Cyclin-dependent Kinase Inhibitor 2A, Isoforms 1/2/3, Cyclin-dependent Kinase 4 Inhibitor A, CDK4I, Multiple Tumor Suppressor 1, MTS-1, p16-INK4a, p16-INK4, p16INK4A, CDKN2, MTS1)
• Alternative technique
  antibodies
• Alternative to gene target
  cyclin-dependent kinase inhibitor 2A, ARF and CDK4I and CDKN2 and CMM2 and INK4 and INK4A and MLM and MTS-1 and MTS1 and P14 and P14ARF and P16 and P16-INK4A and P16INK4 and P16INK4A and P19 and P19ARF and TP16, CDKN2A and IDBG-54547 and ENSG00000147889 and 1029, MDM2/MDM4 family protein binding, nuclei, CDKN2A and IDBG-630043 and ENSBTAG00000034220 and 616369
• Tissue
  tumor

Gene info

• Identity
  HGNC:1787
• Gene
  CDKN2A
• Long gene name
  cyclin dependent kinase inhibitor 2A
• Synonyms gene
  • CDKN2
  • MLM
• Synonyms gene name
  • cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
• Synonyms
  • CDK4I
  • p16
  • INK4a
  • MTS1
  • CMM2
  • ARF
  • p19
  • p14
  • INK4
  • p16INK4a
  • p19Arf
  • p14ARF
• GenBank acession
  • L27211
• Locus
  9p21.3
• Discovery year
  1994-05-19
• Entrez gene record
  1029
• Pubmed identfication
  • 8152487
  • 7606716
• RefSeq identity
  • NM_000077
• VEGA ID
  OTTHUMG00000019686
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_11

Gene info

• Identity
  HGNC:10494
• Gene
  S100A4
• Long gene name
  S100 calcium binding protein A4
• Synonyms gene
  • MTS1
  • CAPL
• Synonyms gene name
  • metastasin 1
  • calcium placental protein
  • S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog)
• Synonyms
  • P9KA
  • 18A2
  • PEL98
  • 42A
  • FSP1
• Synonyms name
  • fibroblast-specific protein-1
  • calvasculin
  • murine placental homolog
• GenBank acession
  • BC016300
• Locus
  1q21.3
• Discovery year
  1989-06-30
• Entrez gene record
  6275
• Pubmed identfication
  • 3155863
• RefSeq identity
  • NM_002961
• Classification
  • S100 calcium binding proteins
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000013546

Gene info

• Identity
  HGNC:23831
• Gene
  CDKN2A-DT
• Long gene name
  CDKN2A divergent transcript
• Synonyms gene
  • C9orf53
  • CDKN2A-AS1
• Synonyms gene name
  • chromosome 9 open reading frame 53
  • CDKN2A antisense RNA 1 (head to head)
• Synonyms
  • bA149I2.3
• GenBank acession
  • AF211119
• Locus
  9p21.3
• Discovery year
  2004-07-23
• Entrez gene record
  51198
• RefSeq identity
  • NR_024274
• Classification
  • Divergent transcripts
• VEGA ID
  OTTHUMG00000019687

Gene info

• Identity
  HGNC:11817
• Gene
  TIMM8A
• Long gene name
  translocase of inner mitochondrial membrane 8A
• Synonyms gene
  • DFN1
• Synonyms gene name
  • translocase of inner mitochondrial membrane 8 (yeast) homolog A
  • translocase of inner mitochondrial membrane 8 homolog A (yeast)
• Synonyms
  • DDP
  • MTS
• GenBank acession
  • U66035
• Locus
  Xq22.1
• Discovery year
  1999-12-01
• Entrez gene record
  1678
• Pubmed identfication
  • 10552927
  • 8841189
• RefSeq identity
  • NM_004085
• VEGA ID
  OTTHUMG00000022028

Gene info

• Identity
  HGNC:1788
• Gene
  CDKN2B
• Long gene name
  cyclin dependent kinase inhibitor 2B
• Synonyms gene name
  • cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
• Synonyms
  • P15
  • MTS2
  • INK4B
  • TP15
  • CDK4I
  • p15INK4b
• GenBank acession
  • AB060808
• Locus
  9p21.3
• Discovery year
  1995-06-14
• Entrez gene record
  1030
• Pubmed identfication
  • 8078588
• RefSeq identity
  • NM_004936
• VEGA ID
  OTTHUMG00000019691

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

Gene info

• Identity
  HGNC:50820
• Gene
  TRUND-NNN8-1
• Long gene name
  tRNA-undetermined (NNN) 8-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 8-1
• GenBank acession
  • HG984097
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482528
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:50819
• Gene
  TRUND-NNN7-1
• Long gene name
  tRNA-undetermined (NNN) 7-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 7-1
• GenBank acession
  • HG984096
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482531
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:5760
• Gene
  IGKV1OR2-1
• Long gene name
  immunoglobulin kappa variable 1/OR2-1 (pseudogene)
• Synonyms gene
  • IGKVPZ1
  • IGKV1OR-1
• Synonyms gene name
  • immunoglobulin kappa variable 1/OR-1
  • immunoglobulin kappa variable 1/OR-1 pseudogene
  • immunoglobulin kappa variable 1/OR-1 (pseudogene)
• Synonyms
  • IGKV1/OR-1
  • IGKV1/OR2-1
• GenBank acession
  • Z12367
• Locus
  2p11.1
• Discovery year
  2000-04-18
• Entrez gene record
  3531
• Pubmed identfication
  • 2853098
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000155081

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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