BMI1 polyclonal antibody

• Catalog number
  6862-50
• Price
  Please ask
• Size
  50 μl

• Antibody Target
  BMI1
• Target Alternative Name
  PCGF4, RNF51, FLVI2
• Antibody Type
  Polyclonal
• Species Reactivities
  Mouse.
• Immunogen Sequence
  Polyclonal antibody raised in rabbit against mouse BMI1 (BMI1 polycomb ring finger oncogene) using two KLH conjugated synthetic peptides containing a sequence from the central and the C-terminal region of the protein, respectively.
• Accession
  P35226
• Gene Id
  100532731. 648.
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In PBS with 0.05% (W/V) sodium azide.
• Purification
  Whole Anti-Sera
• Application
  ELISA.
• Positive Control
  ELISA: Peptides.
• Application And Usages
  ELISA: 1:300.
• Description
  BMI1 (B lymphoma Mo-MLV insertion region 1 homolog) is a core component of the polycomb group (PcG) multiprotein PRC1 complex which plays an important role in transcriptional repression of gene expression during development. BMI1 association with RING protein 1B is important to the E3 ligase activity of RING1B in the PRC1 complex. BMI1 is an oncogene whose overexpression is associated with many types of human tumors and is a stem-cell marker and regulator of stem cell self-renewal.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Not Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  BMI1  
• Gene symbol
  COMMD3-BMI1, BMI1
• Short name
  BMI1 polyclonal antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Rabbit IgG
• Alternative name
  BMI1 polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:48326
• Gene
  COMMD3-BMI1
• Long gene name
  COMMD3-BMI1 readthrough
• Locus
  10p12.2
• Discovery year
  2013-05-08
• Entrez gene record
  100532731
• VEGA ID
  OTTHUMG00000184031

Gene info

• Identity
  HGNC:1066
• Gene
  BMI1
• Long gene name
  BMI1 proto-oncogene, polycomb ring finger
• Synonyms gene
  • PCGF4
• Synonyms gene name
  • polycomb group ring finger 4
  • B lymphoma Mo-MLV insertion region 1 homolog (mouse)
• Synonyms
  • RNF51
• GenBank acession
  • BC011652
• Locus
  10p12.2
• Discovery year
  1994-01-05
• Entrez gene record
  648
• Pubmed identfication
  • 8268912
• RefSeq identity
  • NM_005180
• Classification
  • Polycomb group ring fingers
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000017807

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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