Parathyroid Hormone (PTH) (N- & C-Terminal) Mouse Monoclonal Antibody

• Catalog number
  MBS438908
• Price
  Please ask
• Size
  0.02 mg (With BSA & Azide at 0.2mg/mL)

• Products_type
  Antibody
• Products_short_name
  [Parathyroid Hormone (PTH)]
• Products_name_syn
  [hPTH; Parathormone; Parathyrin; Parathyroid hormone 1 (PTH1); Parathyroid hormone (PTH)]
• Other_names
  [parathyroid hormone isoform 1 preproprotein; Parathyroid hormone; parathyroid hormone; parathyroid hormone; Parathormone; Parathyrin]
• Products_gene_name
  [PTH]
• Other_gene_names
  [PTH; PTH; PTH1; PTH]
• Clonality
  Monoclonal
• Clone
  [3H9 + PTH/1175]
• Reactivity
  Human
• Specificity
  Epitope of this MAb maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
• Form
  200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Storage_stability
  Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Tested_application
  Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  Hormone releasing factors and releasing hormones are  signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Parathyroid   Hormone   PTH   Monoclonal  
• Gene symbol
  PTH
• Short name
  Parathyroid Hormone (PTH) (N- & C-Terminal) Mouse Monoclonal Antibody
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG
• Species
  Mouse, Mouses
• Alternative name
  Parathyroid Hormone (parathyroid hormone) (N- & C-Terminal) Mouse monoclonal (antibody to-)
• Alternative technique
  antibodies, murine
• Alternative to gene target
  parathyroid hormone, PTH1, PTH and IDBG-32891 and ENSG00000152266 and 5741, peptide hormone receptor binding, Extracellular, Pth and IDBG-207092 and ENSMUSG00000059077 and 19226, PTH and IDBG-632953 and ENSBTAG00000019080 and 280903

Gene info

• Identity
  HGNC:9606
• Gene
  PTH
• Long gene name
  parathyroid hormone
• Synonyms
  • PTH1
• Synonyms name
  • parathyrin
  • parathormone
  • parathyroid hormone 1
  • preproparathyroid hormone
  • prepro-PTH
• GenBank acession
  • J00301
• Locus
  11p15.3
• Discovery year
  2001-06-22
• Entrez gene record
  5741
• Pubmed identfication
  • 1672845
• RefSeq identity
  • NM_000315
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000165785

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products