Armenian Hamster CD154 Mouse Monoclonal Antibody [MR1]-Biotin

• Catalog number
  BD-MO154B(V25)
• Price
  Please ask
• Size
  0,025 mg

• Description
  Armenian Hamster CD154 Mouse Monoclonal Antibody [MR1]-Biotin is a mouse monoclonal antibody, specific for [MR1] clones, this product was conjugated with Biotin format and reported for use in flow cytometric analysis to interact with CD154 in activated CD4+ T cells, CD154's function is the costimulation of T-B cells, this antibody inhibits T and B lymphocytes activation in vitro, and blocks lymphocyte responses to specific antigen in vivo.
• Other antibodies
• Clone
  MR1
• Conjugate
  Biotin
• Gene Name
  CD154
• Other Names of gene
  CD40 ligand (CD40L), gp39, T-BAM, TRAP, Ly-62, TNFSF5
• Concentration
  500 µg/mL
• Application
  Flow Cytometry Method
• Immunogen
  Activated mouse Th1 clone D1.18
• Formulation
  Aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3).
• Storage
  2-8°C, store in dark, do not freeze
• Expiration
  After 1 year
• Remark
  For Recherche Use Only.
• Properties
  If you buy Antibodies supplied by Immunostep they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6. Armenian of Syrian hamster monoclonal IgGs are useful antibodies for double staining your IHC samples. Using mabs or monoclonal antibodies has a lot of advantages for Flow cytometry.
• Conjugation
  Biotinylated
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Armenian   CD154   Monoclonal   [MR1]  
• Gene symbol
  MR1, CD40LG
• Short name
  Armenian CD154 Mouse Monoclonal Antibody [MR1]-
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  Hamster, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  Armenian Hamster IgG
• Label
  Biotin
• Species
  Mouse, Hamsters, Mouses
• Alternative name
  Armenian Hamster Anti Mouse CD154 Antibody-Biotin
• Alternative technique
  antibodies, murine
• Alternative to gene target
  major histocompatibility complex, class I-related, HLALS, MR1 and IDBG-105193 and ENSG00000153029 and 3140, peptide antigen binding, Extracellular, Mr1 and IDBG-199690 and ENSMUSG00000026471 and 15064, MR1 and IDBG-636942 and ENSBTAG00000009924 and 506206

Gene info

• Identity
  HGNC:4975
• Gene
  MR1
• Long gene name
  major histocompatibility complex, class I-related
• Synonyms gene
  • HLALS
• Synonyms gene name
  • major histocompatibility complex, class I-like sequence
• GenBank acession
  • AF010446
• Locus
  1q25.3
• Discovery year
  1995-12-20
• Entrez gene record
  3140
• Pubmed identfication
  • 7624800
  • 9784382
• RefSeq identity
  • NM_001531
• Classification
  • C1-set domain containing
  • Minor histocompatibility antigens
• VEGA ID
  OTTHUMG00000035175

Gene info

• Identity
  HGNC:11935
• Gene
  CD40LG
• Long gene name
  CD40 ligand
• Synonyms gene
  • HIGM1
  • IMD3
  • TNFSF5
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome)
• Synonyms
  • CD40L
  • TRAP
  • gp39
  • hCD40L
  • CD154
• Synonyms name
  • CD40 antigen ligand
  • tumor necrosis factor (ligand) superfamily member 5
  • T-B cell-activating molecule
  • TNF-related activation protein
  • hyper-IgM syndrome
• GenBank acession
  • X67878
• Locus
  Xq26.3
• Discovery year
  1989-06-30
• Entrez gene record
  959
• Pubmed identfication
  • 1427881
  • 7678782
• RefSeq identity
  • NM_000074
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000022512
• Locus Specific Databases
  • CD40Lbase: Mutation registry for X-linked Hyper-IgM syndrome
  • Global Variome shared LOVD
  • LRG_141

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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