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Armenian Hamster CD80 Mouse Monoclonal Antibody 16 10A1

Armenian Hamster CD80 Mouse Monoclonal Antibody 16 10A1 is available 15 times from Immunostep labs

BD-MO80A(V100) | Armenian Hamster CD80 Mouse Monoclonal Antibody [16-10A1]-APC size: 0,1 mg | 273.18 USD

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BD-MO80A(V25) | Armenian Hamster CD80 Mouse Monoclonal Antibody [16-10A1]-APC size: 0,025 mg | 90.68 USD

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BD-MO80B(V100) | Armenian Hamster CD80 Mouse Monoclonal Antibody [16-10A1]-Biotin size: 0,1 mg | 50.5 USD

Description Armenian Hamster CD80 Mouse Monoclonal Antibody [16-10A1]-Biotin is a mouse monoclonal antibody, specific for [16-10A1] clones, this product was conjugated with Biotin format and reported for use in flow cytometric analysis to react with CD80 glycosylated proteins that found in macrophages, dendritic cells and also in activated in B and T cells, CD80 plays a role of T cell costimulation.
Conjugate Biotin
Concentration 500 µg/mL
Properties If you buy Antibodies supplied by Immunostep they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.Armenian of Syrian hamster monoclonal IgGs are useful antibodies for double staining your IHC samples. Using mabs or monoclonal antibodies has a lot of advantages for Flow cytometry.
Conjugation Biotinylated
About Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Test Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name Mus musculus
French translation anticorps
Short name Armenian CD80 Mouse Monoclonal Antibody [16-10A1]-
Technique Mouse monoclonal, Antibody, Mouse
Label Biotin
Species Mouse
Alternative name Armenian Hamster CD80 molecule Mouse monoclonal (Antibody to) [16-10A1]-biotinilated
Alternative to gene target CD80 molecule, B7 and B7-1 and B7.1 and BB1 and CD28LG and CD28LG1 and LAB7, CD80 and IDBG-51287 and ENSG00000121594 and 941, coreceptor activity, Cell surfaces, Cd80 and IDBG-160288 and ENSMUSG00000075122 and 12519, BT.27986 and IDBG-632750 and ENSBTAG00000018059 and 407131
1. Gene info
Identity37586
GenePIRC82
Long gene name piwi-interacting RNA cluster 82
Locus16
Discovery year 2009-11-05
Entrez gene record100313933
Pubmed identfication
Classification
  • Piwi-interacting RNA clusters
2. Gene info
Identity1700
GeneCD80
Long gene name CD80 molecule
Synonyms gene
Synonyms gene name
  • CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)
  • CD80 molecule
Synonyms
Locus3q13.33
Discovery year 1993-12-14
Entrez gene record941
Pubmed identfication
RefSeq identity
Classification
  • C2-set domain containing
  • CD molecules
  • V-set domain containing
Havana BLAST/BLATOTTHUMG00000159419
MeSH Data
Concept
Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Additional information
PubMedB7-1/B7-2 costimulation regulates plaque T-cell responses and atherogenesis.
B7-1 in podocytes was found in genetic, drug-induced, immune-mediated, and bacterial toxin-induced experimental kidney diseases with nephrotic syndrome.
Increased B7-1 expression on islet-infiltrated nonobese diabetic (NOD) mouse B cells is associated with increased T cell costimulation and the development of inflammatory insulitis in NOD mice.
CTLA4-CD80/CD86 interactions on T cells integrate signal strength, based on the dose of Con A, to enhance or inhibit primary mouse CD4(+) T cell cycling and survival.
Regulation delivered by splice variants of CD80 significantly modulates heart transplantation immunity and may be common across the species.
Data indicate that anti-B7-1 monoclonal antibody can trigger innate-effector responses in macrophages by activating NF-kappaB, and B7 molecules are not only essential for induction of adaptive immune responses but also play roles in innate immunity.
B7-1 and PD-L1 are identified as binding partners; functional studies indicate that the B7-1:PD-L1 interaction can inhibit T cell proliferation and cytokine production.
surprising role for interactions of CTLA-4 expressed by alloreactive peripheral CD4 T cells with CD80/86 on recipient antigen-presenting cells (APCs) in the induction of early tolerance
Splenic and PerC B cells revealed a distinctive pattern in their mode of expressing costimulatory molecules when challenged by exogenous or endogenous antigens
B7 as an essential costimulatory molecule in the generation of Mycobacterium tuberculosis-specific T helper cell (Th)1 type response and formation of the tubercle granuloma.
Gene ontology - Molecular functionprotein binding
Entrez GeneCD80 antigen  (CD80)
Product images
    #Mouse#.jpg

BD-MO80B(V25) | Armenian Hamster CD80 Mouse Monoclonal Antibody [16-10A1]-Biotin size: 0,025 mg | 148.07 USD

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BD-MO80CFB(V100) | Armenian Hamster CD80 Mouse Monoclonal Antibody [16-10A1]-CF-Blue™ size: 0,1 mg | 313.35 USD

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BD-MO80CFB(V25) | Armenian Hamster CD80 Mouse Monoclonal Antibody [16-10A1]-CF-Blue™ size: 0,025 mg | 113.63 USD

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BD-MO80F(V25) | Armenian Hamster CD80 Mouse Monoclonal Antibody [16-10A1]-FITC size: 0,025 mg | 78.05 USD

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BD-MO80F(V100) | Armenian Hamster CD80 Mouse Monoclonal Antibody [16-10A1]-FITC size: 0,1 mg | 136.59 USD

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BD-MO80F (V500) | Armenian Hamster CD80 Mouse Monoclonal Antibody [16-10A1]-FITC size: 0,5 mg | 210.05 USD

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BD-MO80PE(V25) | Armenian Hamster CD80 Mouse Monoclonal Antibody [16-10A1]-PE size: 0,025 mg | 67.72 USD

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BD-MO80PE(V100) | Armenian Hamster CD80 Mouse Monoclonal Antibody [16-10A1]-PE size: 0,1 mg | 142.33 USD

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BD-MO80PP(V100) | Armenian Hamster CD80 Mouse Monoclonal Antibody [16-10A1]-PerCP size: 0,1 mg | 301.87 USD

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BD-MO80PP5.5(V100) | Armenian Hamster CD80 Mouse Monoclonal Antibody [16-10A1]-PerCP-Cyanine5.5 size: 0,1 mg | 313.35 USD

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BD-MO80PP5.5(V25) | Armenian Hamster CD80 Mouse Monoclonal Antibody [16-10A1]-PerCP-Cyanine5.5 size: 0,025 mg | 113.63 USD

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BD-MO80PU (V500) | Armenian Hamster CD80 Mouse Monoclonal Antibody [16-10A1]-PURE size: 0,5 mg | 221.53 USD

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Storage 2-8°C, store in dark, do not freeze
Gene Name CD80
Formulation Aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3).
Immunogen Mouse CD80 (B7) Transfected Cell Line
Expiration After 1 year
Other Names of gene B7-1, Ly-53, MIC17, TSA1
Application Flow Cytometry Method
Clone 16-10A1
Remark For Recherche Use Only.
Host Hamster
Alternative technique antibodies
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