SOX2 Antibody

• Catalog number
  F47908-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS pH 7.4 with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  SOX2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, IF, FACS, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
• Notes
  Titration of the SOX-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This SOX-2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P48431
• Purity
  Purified
• Description
  The intronless gene for SOX2 encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.
• Immunogen
  A portion of amino acids 89-119 from the human protein was used as the immunogen for this SOX-2 antibody.
• Storage
  Aliquot the SOX-2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SOX2  
• Gene symbol
  SOX2, SOX2-OT
• Short name
  Anti-SOX2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to SOX2
• Alternative technique
  antibodies
• Alternative to gene target
  SRY (sex determining region Y)-box 2, ANOP3 and MCOPS3, SOX2 and IDBG-66692 and ENSG00000181449 and 6657, protein heterodimerization activity, nuclei, Sox2 and IDBG-137912 and ENSMUSG00000074637 and 20674, SOX2 and IDBG-647279 and ENSBTAG00000011598 and 784383

Gene info

• Identity
  HGNC:11195
• Gene
  SOX2
• Long gene name
  SRY-box transcription factor 2
• Synonyms gene name
  • SRY (sex determining region Y)-box 2
  • SRY-box 2
• GenBank acession
  • BC013923
• Locus
  3q26.33
• Discovery year
  1993-11-30
• Entrez gene record
  6657
• Pubmed identfication
  • 7849401
• RefSeq identity
  • NM_003106
• Classification
  • SRY-box transcription factors
• VEGA ID
  OTTHUMG00000158222
• Locus Specific Databases
  • LOVD
  • LRG_719

Gene info

• Identity
  HGNC:20209
• Gene
  SOX2-OT
• Long gene name
  SOX2 overlapping transcript
• Synonyms gene
  • SOX2OT
• Synonyms gene name
  • SOX2 overlapping transcript (non-protein coding)
• Synonyms
  • DKFZp761J1324
  • NCRNA00043
• Synonyms name
  • non-protein coding RNA 43
• GenBank acession
  • AL157425
  • AK022826
• Locus
  3q26.33
• Discovery year
  2003-07-01
• Entrez gene record
  347689
• Pubmed identfication
  • 12612584
  • 19767420
  • 28960757
• RefSeq identity
  • NR_004053
• Classification
  • Overlapping transcripts
• VEGA ID
  OTTHUMG00000158186

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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