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anti-Anti- STAT1 Antibody

anti-Anti- STAT1 Antibody is available 1 time from Biovision labs

A1215-100 | anti-Anti- STAT1 Antibody size: Anti- STAT1 Antibody | 471.67 USD

Catalog number A1215-100
Supplier Biovision
Price 471.67 USD
Size Anti- STAT1 Antibody
1. Gene info
Identity 11362
Gene STAT1
Long gene name signal transducer and activator of transcription 1
Synonyms gene name
  • signal transducer and activator of transcription 1, 91kD
  • signal transducer and activator of transcription 1, 91kDa
Synonyms
  • STAT91
  • ISGF-3
Synonyms name
  • transcription factor ISGF-3 components p91/p84
Locus 2q32.2
Discovery year 1995-11-08
Entrez gene record 6772
Pubmed identfication
  • 7885841
RefSeq identity
  • NM_007315
Classification
  • SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000132699
Locus Specific Databases
  • STAT1base: Mutation registry for STAT1 deficiency
  • LRG_111
Product images
    #0#.jpegAnti- STAT1 Antibody
Target of this antibody: STAT1
Alternative names of antibody target: Signal transducer and activator of transcription 1-alpha/beta; Transcription factor ISGF-3 components p91/p84
Background information: Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
Clone: N/A
This antibody reacts with: Human, Mouse, Rat
Immunogene sequence: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human STAT1
Form of antibody: Liquid
Formulation of this antibody: In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
Purification method: Affinity purified
This antibody has been succesfully tested for use in following methods: WB
Recommended usage: WB; 1:500 – 1:2000
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetAnti STAT1
Short name anti-Anti- STAT1 Antibody
Technique Antibody, anti-, anti
Alternative name antibody to-Antibody to signal transducer and activator on transcription 1, 91kDa (Antibody to)
Alternative technique antibodies
Alternative to gene target signal transducer and activator of transcription 1, 91kDa, CANDF7 and IMD31A and IMD31B and IMD31C and ISGF-3 and STAT91, STAT1 and IDBG-77617 and ENSG00000115415 and 6772, sequence-specific DNA binding, nuclei, Stat1 and IDBG-153162 and ENSMUSG00000026104 and 20846, STAT1 and IDBG-642654 and ENSBTAG00000007867 and 510814,515988
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