SUMO1 Antibody

• Catalog number
  F42001-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  SUMO1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, FACS, IF, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
• Notes
  Titration of the SUMO1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This SUMO1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P63165
• Purity
  Purified
• Description
  Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. The SUMO family consists of SUMO1 and closely related homologs SUMO2, SUMO3, and SUMO4. Sumoylation has been shown to regulate a wide range of proteins, including MDM2, PIAS, PML, RanGAP1, RanBP2, p53, p73, HIPK2, TEL, c-Jun, Fas, Daxx, TNFRI, Topo-I, Topo-II, PARK2, WRN, Sp100, IkB-alpha, Androgen receptor (AR), GLUT1/4, CaMK, DNMT3B, TDG, HIF1A, CHD3, EXOSC9, RAD51, and viral targets such as CMV-IE1/2, EBV-BZLF1, and HPV/BPV-E1.
• Immunogen
  A portion of amino acids 1-30 from the human protein was used as the immunogen for this SUMO1 antibody.
• Storage
  Aliquot the SUMO1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SUMO1  
• Gene symbol
  SUMO1
• Short name
  Anti-SUMO1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to SUMO1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:12502
• Gene
  SUMO1
• Long gene name
  small ubiquitin like modifier 1
• Synonyms gene
  • UBL1
• Synonyms gene name
  • ubiquitin-like 1 (sentrin)
  • SMT3 suppressor of mif two 3 homolog 1 (yeast)
  • SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
• Synonyms
  • PIC1
  • GMP1
  • SMT3C
  • SUMO-1
  • SMT3H3
  • OFC10
• GenBank acession
  • U38784
• Locus
  2q33.1
• Discovery year
  1996-06-04
• Entrez gene record
  7341
• Pubmed identfication
  • 8812453
  • 8906799
• RefSeq identity
  • NM_003352
• VEGA ID
  OTTHUMG00000132839

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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