Ubiquitin-TAMRA-labeled (TMR-Ub)

• Catalog number
  7553-50
• Price
  Please ask
• Size
  50 ug

• Synonyms
  UBB, Ribosomal Protein S27a, CEP80, UBA80, UBCEP1, UBCEP80, HUBCEP80, RPS27A.
• Alternative_names
  UBB, Ribosomal Protein S27a, CEP80, UBA80, UBCEP1, UBCEP80, HUBCEP80, RPS27A.
• Description
  Substrate to determine the activity of ubiquitin conjugating enzymes
• Purity by SDS PAGE
  ≥95%
• Assay
  RP-HPLC
• Molecular Weight
  9.133 kDa
• Storage Temp
  -80°C
• Shipping
  Dry Ice
• Shelf Life
  12 months
• Concentration
  ≥ 8 mg/mL
• Appearance
  Liquid
• Physical form description
  ≥ 8 mg/mL in PBS
• Background Information
  Post-translational modification of proteins by ubiquitin (Ub) is a key regulatory process that impacts almost all cellular functions. Ubiquitylation occurs through isopeptide linkage between the C-terminus of Ub and the e-amino group of a lysine (Lys) residue on the target substrate [1]. Ub itself has seven Lys residues (6, 11, 27, 29, 33, 48, and 63), any of which can participate in further ubiquitylation, generating polyUb chains [2, 3]. Monitoring the ubiquitylation of target proteins or the growth of polyubiquitin chains has traditionally been carried out with either radiolabeled or epitope-tagged ubiquitin requiring long and laborious detection methods. Fluorescently labeled ubiquitin provides a rapid, facile technique for studying ubiquitin conjugation in vitro. Unlike others, BioVision’s TAMRA-labeled ubiquitin carries a single TAMRA molecule attached at a defined location and avoids modification of either the N-terminus or Lys side chains.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Additional description
  FITC labelling for flow cytometry of antibodies and peptides.

• Gene target
  Ubiquitin-TAMRA   TMR-Ub  
• Short name
  Ubiquitin-TAMRA- (TMR-Ub)
• Label
  TAMRA
• Alternative name
  Ubiquitin-TAMRA-labeled (TMR-Ub)

MeSH Data

• Name
  Drug Labeling
• Concept
  Scope note: Use of written, printed, or graphic materials upon or accompanying a drug container or wrapper. It includes contents, indications, effects, dosages, routes, methods, frequency and duration of administration, warnings, hazards, contraindications, side effects, precautions, and other relevant information.
• Tree numbers
  • E05.916.310
• Qualifiers
  trends, ethics, history, classification, economics, instrumentation, methods, standards, legislation & jurisprudence, statistics & numerical data

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