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anti-ZBTB7/Pokemon Antibody

anti-ZBTB7/Pokemon Antibody is available 1 time from Biovision labs

3791-100 | anti-ZBTB7/Pokemon Antibody size: ZBTB7/Pokemon Antibody | 400.60 USD

Catalog number 3791-100
Supplier Biovision
Price 400.60 USD
Size ZBTB7/Pokemon Antibody
1. Gene info
Identity 18078
Gene ZBTB7A
Long gene name zinc finger and BTB domain containing 7A
Synonyms gene
  • ZBTB7
Synonyms gene name
  • zinc finger and BTB domain containing 7
Synonyms
  • FBI-1
  • LRF
  • DKFZp547O146
  • pokemon
  • ZNF857A
Synonyms name
  • zinc finger and BTB domain containing 7A, HIV-1 inducer of short transcripts binding protein
  • lymphoma related factor
GenBank acession
  • AF000561
Locus 19p13.3
Discovery year 2004-01-16
Entrez gene record 51341
Pubmed identfication
  • 9973611
  • 9927193
RefSeq identity
  • NM_015898
Classification
  • BTB domain containing
  • Zinc fingers C2H2-type
Havana BLAST/BLAT OTTHUMG00000181792
Product images
    #0#.jpeg
Target of this antibody: ZBTB7
Alternative names of antibody target: Pokemon, FBI1, FBI-1, Factor that Binds to Inducer of Short Transcripts (IST) protein 1, LRF, Leukemia/lymphoma Related Factor, ZBTB7, ZBTB7A, Zinc Finger and BTB domain containing 7A, TIP21, TIP-21, TTF-1 interacting peptide 21, OCZF, Osteoclast Derived
Background information: Zinc finger and BTB domain-containing protein 7A (LRF, Pokemon, FBI1) is a transcriptional repressor encoded by the ZBTB7A gene that belongs to the POK (POZ and Kruppel)/ZBTB (zinc finger and BTB) family. LRF is broadly expressed with elevated expression in a variety of cancers relative to normal tissues, including non-small cell lung cancer, breast cancer, ovarian cancer, prostate cancer, and hepatocellular carcinoma. Research studies suggest that LRF acts as an oncogene through various mechanisms including repression of the tumor suppressors ARF and Rb, and repression of the cell cycle arrest factor p21Cip1. The LRF transcription factor plays key roles during several stages of hematopoiesis including promoting lymphoid progenitor cells to commit to B cell differentiation by repressing T cell-promoting Notch signals, and promoting cell survival during terminal erythroid differentiation through suppression of the proapoptotic factor Bim.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
This antibody reacts with: Human, mouse
Immunogene sequence: Synthetic peptide of human ZBTB7 (FBI-1)
Concentration of antibody: N/A
Form of antibody: Liquid
Formulation of this antibody: 100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Purification method: Affinity purified
This antibody has been succesfully tested for use in following methods: Western blot, Immunoprecipitation
Recommended usage: Western blotting (1:500 – 1:2000) and Immunoprecipitation. HeLa cell lysate can be used as a positive control. However, the optimal concentrations should be determined individually. The antibody recognizes the ZBTB7 (BFI-1) of human and mouse origins. Reactivity to other species has not been tested.
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetZBTB7/Pokemon
Short name anti-ZBTB7/Pokemon Antibody
Technique Antibody, anti
Alternative name antibody to-ZBTB7/Pokemon (Antibody to)
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