NOX4 Antibody

• Catalog number
  F43447-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  NOX4
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
• Notes
  Titration of the NOX4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This NOX4 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9NPH5
• Purity
  Antigen affinity
• Description
  This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
• Immunogen
  A portion of amino acids 124-153 from the human protein was used as the immunogen for this NOX4 antibody.
• Storage
  Aliquot the NOX4 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NOX4  
• Gene symbol
  NOX4
• Short name
  Anti-NOX4
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to NOX4
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7891
• Gene
  NOX4
• Long gene name
  NADPH oxidase 4
• Synonyms
  • KOX-1
  • KOX
• GenBank acession
  • AF254621
• Locus
  11q14.3
• Discovery year
  2000-05-30
• Entrez gene record
  50507
• RefSeq identity
  • NM_016931
• VEGA ID
  OTTHUMG00000167298

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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