Recombinant Human Phosphatidylinositol 4-Kinase β/PI4KB Protein(C-6His)

• Catalog number
  PKSH032015-10µg
• Price
  Please ask
• Size
  10µg

• Synonym
  Phosphatidylinositol 4-Kinase Beta; PI4K-Beta; PI4KBeta; PtdIns 4-Kinase Beta; NPIK; PI4K92; PI4KB; PIK4CB
• Activity
  NA
• Sequence
  Met1-Met801
• Fusion tag
  C-6His
• Accession
  Q9UBF8-2
• Expressed Host
  Human cells
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞95% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
• Mol Mass
  90.8 kDa
• AP Mol Mass
  95 kDa
• Formulation
  Supplied as a 0.2 μm filtered solution of 25mM TrisHCl,100mM glycine,10%glycerol,pH7.3.
• Background
  Phosphatidylinositol 4-Kinase β (PI4KB) belongs to the PI3/PI4-kinase family and Type III PI4K subfamily. PI4KB contains one PI3K/PI4K domain and one PIK helical domain. It is highly expressed in heart, skeletal muscle, pancreas, testis and ovary,; it is lowly expressed in liver tissue. PI4KB kinase activity can be inhibited by wortmannin, and increased by interacting with NCS1/FREQ. PI4KB phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). In addition, PI4KB may regulate Golgi disintegration/reorganization during mitosis.
• Technical data
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Phosphatidylinositol   4-Kinase   β/PI4KB   Protein   C-6His  
• Gene symbol
  PI4KB
• Short name
  Recombinant Phosphatidylinositol 4-Kinase β/PI4KB Protein(C-6His)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Phosphatidylinositol 4-phosphorylation catalyst β/phosphatidylinositol 4-kinase, catalytic, b Protein(C-6His)
• Alternative technique
  rec
• Alternative to gene target
  phosphatidylinositol 4-kinase, catalytic, beta, NPIK and PI4K-BETA and PI4K92 and PI4KBETA and PI4KIIIBETA and PIK4CB, PI4KB and IDBG-102347 and ENSG00000143393 and 5298, transferase activity, Plasma membranes, Pi4kb and IDBG-171130 and ENSMUSG00000038861 and 107650, PI4KB and IDBG-633134 and ENSBTAG00000007320 and 286846

Gene info

• Identity
  HGNC:8984
• Gene
  PI4KB
• Long gene name
  phosphatidylinositol 4-kinase beta
• Synonyms gene
  • PIK4CB
• Synonyms gene name
  • phosphatidylinositol 4-kinase, catalytic, beta
• Synonyms
  • PI4K-BETA
  • pi4K92
• GenBank acession
  • AB005910
• Locus
  1q21.3
• Discovery year
  1998-04-07
• Entrez gene record
  5298
• Pubmed identfication
  • 9020160
  • 9405938
• RefSeq identity
  • NM_002651
• VEGA ID
  OTTHUMG00000012348

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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