MI-3 (Menin-MLL Inhibitor)
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Catalog numberM341040
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PricePlease ask
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Size5 mg
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Chemical available in other sizesPlease inquire size and price
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Stock availabilityPlease Inquire
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Cas number1271738-59-0
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Chemical s molecular weight375.55
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Chemical s main applicationsMI-3 (Menin-MLL Inhibitor) reverses oncogenic activity of MLL fusion proteins in leukemia.
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Chemical s categoryAromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
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Other name4-[4-(4,5-Dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-(1-methylethyl)-thieno[2,3-d]pyrimidine;
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Chemical s formulaC18H25N5S2
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Physical propertiesNo Data Available
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Melting temperatureNo Data Available
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Boiling temperatureNo Data Available
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Chemical s soluble inNo Data Available
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Stability conditionsNo Data Available
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StorageNo Data Available
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DescriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbolKMT2A, MITF, CHD4, MIER1, CHD3, MIR1302-3, MIR509-3, MIR7-3, PIRC14
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Short nameMI-3 (Menin-MLL Inhibitor)
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Alternative nameMI-3 (Menin-myeloid/lymphoid and mixed-lineage leukemia (trithorax homolog, Drosophila) suppressor)
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Alternative to gene targetmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), ALL-1 and CXXC7 and HRX and HTRX1 and MLL and MLL/GAS7 and MLL1 and MLL1A and TET1-MLL and TRX1 and WDSTS, MLL and IDBG-73725 and ENSG00000118058 and 4297, lysine-acetylated histone binding, nuclei, Mll1 and IDBG-158453 and ENSMUSG00000002028 and 214162, MLL and IDBG-631302 and ENSBTAG00000018093 and 508330
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Gene info
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Identity
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Gene
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Long gene namelysine methyltransferase 2A
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Synonyms gene
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Synonyms gene name
- myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog)
- myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
- lysine (K)-specific methyltransferase 2A
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-11-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PHD finger proteins
- SET domain containing
- Lysine methyltransferases
- Zinc fingers CXXC-type
- Bromodomain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemelanocyte inducing transcription factor
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Synonyms gene
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Synonyms gene name
- Waardenburg syndrome, type 2A
- microphthalmia-associated transcription factor
- melanogenesis associated transcription factor
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Synonyms
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Synonyms name
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Locus
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Discovery year1993-10-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Basic helix-loop-helix proteins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namechromodomain helicase DNA binding protein 4
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-03-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- NuRD complex subunits
- PHD finger proteins
- Small nucleolar RNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameMIER1 transcriptional regulator
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Synonyms gene name
- mesoderm induction early response 1 homolog (Xenopus laevis)
- mesoderm induction early response 1, transcriptional regulator
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Synonyms
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Locus
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Discovery year2005-07-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Myb/SANT domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namechromodomain helicase DNA binding protein 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-03-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNA protein coding host genes
- NuRD complex subunits
- PHD finger proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1302-3
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1302 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 509-3
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Synonyms gene
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Synonyms
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Locus
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Discovery year2007-10-24
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR506 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 7-3
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR7 family
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 14
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters