1-[3-[1-([1,1'-Biphenyl]-3-ylmethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
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Catalog numberB522600
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PricePlease ask
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Size25 mg
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Chemical available in other sizesPlease inquire size and price
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Stock availabilityPlease Inquire
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Cas number1380088-03-8
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Chemical s molecular weight555.03
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Chemical s main applications1-[3-[1-([1,1'-Biphenyl]-3-ylmethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a highly selective and cell permeable c-Src kinase inhibitor. c-Src is a a key signaling kinase in cancer and this compound shows promising therapeutic potential, significantly more so than pan-kinase inhibiitors, in the treatment of cancers.
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Chemical s categoryAromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors,
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Chemical s formulaC32H23ClN8
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Physical propertiesNo Data Available
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Melting temperatureNo Data Available
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Boiling temperatureNo Data Available
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Chemical s soluble inNo Data Available
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Stability conditionsNo Data Available
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StorageNo Data Available
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Gene target
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Gene symbolVSIR, IGHVIII-5-1, TRX-CAT1-4, TRI-AAT5-4, IGHV7-4-1, TRY-GTA5-1, TSPAN5, NTF4, HCG4P5
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Short name1-[3-[1-([1 1'-Biphenyl]-3-ylmethyl)-1H-1 2 3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3 4-d]pyrimidin-4-amine
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Alternative name1-[3-[1-([1,1'-Biphenyl]-3-ylmethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
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Gene info
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Identity
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Gene
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Long gene nameV-set immunoregulatory receptor
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Synonyms gene
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Synonyms gene name
- chromosome 10 open reading frame 54
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2005-10-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- B7 family
- V-set domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (III)-5-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (III)-5-1
- immunoglobulin heavy variable (III)-5-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametRNA-iMet (anticodon CAT) 1-4
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Synonyms gene
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Synonyms gene name
- transfer RNA methionine 4 (anticodon CAU)
- transfer RNA-iMet (CAT) 1-5
- transfer RNA-iMet (CAT) 1-4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 5-4
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 15 (anticodon AAU)
- transfer RNA-Ile (AAT) 5-1
- transfer RNA-Ile (AAT) 5-4
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable 7-4-1
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GenBank acession
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Locus
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Discovery year2000-04-04
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametRNA-Tyr (anticodon GTA) 5-1
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Synonyms gene
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Synonyms gene name
- transfer RNA tyrosine 15 (anticodon GUA)
- transfer RNA-Tyr (GTA) 5-4
- transfer RNA-Tyr (GTA) 5-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametetraspanin 5
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Synonyms gene
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Synonyms gene name
- transmembrane 4 superfamily member 9
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Synonyms
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Locus
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Discovery year2003-07-21
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Entrez gene record
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RefSeq identity
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Classification
- Tetraspanins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameneurotrophin 4
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Synonyms gene
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Synonyms gene name
- neurotrophin 5 (neurotrophin 4/5)
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Synonyms
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Synonyms name
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Locus
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Discovery year1992-10-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Neurotrophins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameHLA complex group 4 pseudogene 5
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Synonyms
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Synonyms name
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Locus
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Discovery year2003-09-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: An in vitro allergen radioimmunoassay in which allergens are coupled to an immunosorbent. The coupled allergens bind the IgE in the sera of patients which in turn binds radioisotope-labeled anti-IMMUNOGLOBULIN E antibodies.
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Tree numbers
- E01.370.225.812.735.830
- E05.200.812.735.830
- E05.478.566.380.810
- E05.478.566.639.810
- E05.478.594.760.830
- E05.601.470.380.810
- E05.601.470.639.810
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Qualifiersethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data