1-[3-[1-([1,1'-Biphenyl]-3-ylmethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

• Catalog number
  B522600
• Price
  Please ask
• Size
  25 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  Please Inquire
• Cas number
  1380088-03-8
• Chemical s molecular weight
  555.03
• Chemical s main applications
  1-[3-[1-([1,1'-Biphenyl]-3-ylmethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a highly selective and cell permeable c-Src kinase inhibitor. c-Src is a a key signaling kinase in cancer and this compound shows promising therapeutic potential, significantly more so than pan-kinase inhibiitors, in the treatment of cancers.
• Chemical s category
  Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors,
• Chemical s formula
  C32H23ClN8
• Physical properties
  No Data Available
• Melting temperature
  No Data Available
• Boiling temperature
  No Data Available
• Chemical s soluble in
  No Data Available
• Stability conditions
  No Data Available
• Storage
  No Data Available
• Chemical s specifications

• Gene target
  Biphenyl]   3-ylmethyl   1H-1   3-triazol-5-yl]phenyl]   4-chlorophenyl   1H-pyrazolo[3   4-d]pyrimidin-4-amine  
• Gene symbol
  VSIR, IGHVIII-5-1, TRX-CAT1-4, TRI-AAT5-4, IGHV7-4-1, TRY-GTA5-1, TSPAN5, NTF4, HCG4P5
• Short name
  1-[3-[1-([1 1'-Biphenyl]-3-ylmethyl)-1H-1 2 3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3 4-d]pyrimidin-4-amine
• Alternative name
  1-[3-[1-([1,1'-Biphenyl]-3-ylmethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Gene info

• Identity
  HGNC:30085
• Gene
  VSIR
• Long gene name
  V-set immunoregulatory receptor
• Synonyms gene
  • C10orf54
• Synonyms gene name
  • chromosome 10 open reading frame 54
• Synonyms
  • SISP1
  • GI24
  • B7-H5
  • B7H5
  • VISTA
  • PD-1H
  • Dies1
• Synonyms name
  • stress induced secreted protein 1
  • V-domain Ig suppressor of T cell activation
  • PDCD1 homolog
• GenBank acession
  • AF193048
• Locus
  10q22.1
• Discovery year
  2005-10-06
• Entrez gene record
  64115
• Pubmed identfication
  • 12975309
  • 24691993
  • 25279955
• RefSeq identity
  • NM_022153
• Classification
  • B7 family
  • V-set domain containing
• VEGA ID
  OTTHUMG00000018426

Gene info

• Identity
  HGNC:5702
• Gene
  IGHVIII-5-1
• Long gene name
  immunoglobulin heavy variable (III)-5-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (III)-5-1
  • immunoglobulin heavy variable (III)-5-1 pseudogene
• Synonyms
  • IGHV(III)-5-1
• GenBank acession
  • AB019440
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28354
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152274

Gene info

• Identity
  HGNC:34599
• Gene
  TRX-CAT1-4
• Long gene name
  tRNA-iMet (anticodon CAT) 1-4
• Synonyms gene
  • TRNAM4
  • TRX-CAT1-5
• Synonyms gene name
  • transfer RNA methionine 4 (anticodon CAU)
  • transfer RNA-iMet (CAT) 1-5
  • transfer RNA-iMet (CAT) 1-4
• Synonyms
  • tRNA-iMet-CAT-1-4
• Synonyms name
  • transfer RNA initiator methionine (CAT) 1-5
• GenBank acession
  • HG984140
• Locus
  6p22.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189040
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34839
• Gene
  TRI-AAT5-4
• Long gene name
  tRNA-Ile (anticodon AAT) 5-4
• Synonyms gene
  • TRNAI15
  • TRI-AAT5-1
• Synonyms gene name
  • transfer RNA isoleucine 15 (anticodon AAU)
  • transfer RNA-Ile (AAT) 5-1
  • transfer RNA-Ile (AAT) 5-4
• Synonyms
  • tRNA-Ile-AAT-5-4
• GenBank acession
  • HG983847
• Locus
  14q32.31
• Discovery year
  2008-08-29
• Entrez gene record
  100189275
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:5665
• Gene
  IGHV7-4-1
• Long gene name
  immunoglobulin heavy variable 7-4-1
• GenBank acession
  • L10057
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  57289
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000191141

Gene info

• Identity
  HGNC:35007
• Gene
  TRY-GTA5-1
• Long gene name
  tRNA-Tyr (anticodon GTA) 5-1
• Synonyms gene
  • TRNAY15
  • TRY-GTA5-4
• Synonyms gene name
  • transfer RNA tyrosine 15 (anticodon GUA)
  • transfer RNA-Tyr (GTA) 5-4
  • transfer RNA-Tyr (GTA) 5-1
• Synonyms
  • tRNA-Tyr-GTA-5-1
• GenBank acession
  • HG984081
• Locus
  8q13.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189437
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:17753
• Gene
  TSPAN5
• Long gene name
  tetraspanin 5
• Synonyms gene
  • TM4SF9
• Synonyms gene name
  • transmembrane 4 superfamily member 9
• Synonyms
  • Tspan-5
  • NET-4
• Locus
  4q23
• Discovery year
  2003-07-21
• Entrez gene record
  10098
• RefSeq identity
  • NM_005723
• Classification
  • Tetraspanins
• VEGA ID
  OTTHUMG00000131008

Gene info

• Identity
  HGNC:8024
• Gene
  NTF4
• Long gene name
  neurotrophin 4
• Synonyms gene
  • NTF5
• Synonyms gene name
  • neurotrophin 5 (neurotrophin 4/5)
• Synonyms
  • NT-4/5
  • GLC1O
• Synonyms name
  • neurotrophic factor 4
• Locus
  19q13.33
• Discovery year
  1992-10-15
• Entrez gene record
  4909
• Pubmed identfication
  • 1496419
• RefSeq identity
  • NM_006179
• Classification
  • Neurotrophins
• VEGA ID
  OTTHUMG00000191728

Gene info

• Identity
  HGNC:22925
• Gene
  HCG4P5
• Long gene name
  HLA complex group 4 pseudogene 5
• Synonyms
  • HCGIV-05
  • HCGIV.4
  • HCGIV-5
• Synonyms name
  • HCGIV-05 pseudogene
• Locus
  6p21.3
• Discovery year
  2003-09-01
• Entrez gene record
  353003
• Pubmed identfication
  • 10557312
• RefSeq identity
  • NG_016115
• VEGA ID
  OTTHUMG00000031152

MeSH Data

• Name
  Radioallergosorbent Test
• Concept
  Scope note: An in vitro allergen radioimmunoassay in which allergens are coupled to an immunosorbent. The coupled allergens bind the IgE in the sera of patients which in turn binds radioisotope-labeled anti-IMMUNOGLOBULIN E antibodies.
• Tree numbers
  • E01.370.225.812.735.830
  • E05.200.812.735.830
  • E05.478.566.380.810
  • E05.478.566.639.810
  • E05.478.594.760.830
  • E05.601.470.380.810
  • E05.601.470.639.810
• Qualifiers
  ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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