Hepatitis B virus X protein Antibody, ALEXA FLUOR 350

• Catalog number
  bs-2147R-A350
• Price
  Please ask
• Size
  100ul

• Long name
  Hepatitis B virus X protein Antibody, ALEXA FLUOR 350 Conjugated
• Also known as
  Anti-Hepatitis B virus X protein PAb ALEXA FLUOR 350
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 350
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Hepatitis B virus X protein
• Specificity
  This is a highly specific antibody against Hepatitis B virus X protein.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  10-60/210
• Source
  KLH conjugated synthetic peptide derived from Hepatitis B virus X protein
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Virus
• Cross reactive species details
  Hepatitis B virus
• Background of the antigen
  Multifunctional protein that may modulate protein degradation pathways, apoptosis, transcription, signal transduction, cell cycle progress, and genetic stability by directly or indirectly interacting with hosts factors. Does not seem to be essential for HBV infection. May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma). Most of cytosolic activities involve modulation of cytosolic calcium. The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted. By binding to human DDB1, may affect cell viability and stimulate genome replication. May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential. May also modulate apoptosis by binding human CFLAR, a key regulator of the death-inducing signaling complex (DISC). Moderately stimulates transcription of many different viral and cellular transcription elements. Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT. May bind bZIP transcription factors like CREB1 (By similarity).
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  343nm/442nm
• Synonyms
  HBX; pre-X protein; HB-X; X protein; HBV X protein; X protein [Hepatitis B virus].
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 350
• Description
  Hepatitis a, b, c, d, e recombinant surface viral antigens to genotype 1, 2, 3, 4, 5 are used for antibody production to make diagnostic poly or monoclonal antibodies. Hepatitis is a disease of the liver characterized by the presence of inflammatory cells in the tissue of the organ. Hepatitis may occur without symptoms, but can lead to jaundice (a yellow discoloration of the skin, mucous membranes, and conjunctiva of the eyes), poor appetite, and fatigue. Depending on the cause, hepatitis can manifest either as an acute or as a chronic disease.
• French translation
  anticorps

• Gene target
  Hepatitis   virus   protein  
• Gene symbol
  LAMTOR5P1, LAMTOR5, RSF1
• Short name
  Anti-Hepatitis B virus X protein
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 350
• Species
  Virus, Viruses
• Alternative name
  Hepatitis B virus X protein Antibody, ALEXA FLUOR 350
• Alternative technique
  antibodies
• Virus
  hepatitis

Gene info

• Identity
  HGNC:31854
• Gene
  LAMTOR5P1
• Long gene name
  late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 pseudogene 1
• Synonyms gene
  • HBXIPP1
• Synonyms gene name
  • hepatitis B virus x interacting protein pseudogene 1
• Synonyms
  • HBXIPL
• Synonyms name
  • hepatitis B virus x interacting protein-like
• Locus
  1p31.3
• Discovery year
  2010-06-17
• VEGA ID
  OTTHUMG00000008916

Gene info

• Identity
  HGNC:17955
• Gene
  LAMTOR5
• Long gene name
  late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
• Synonyms gene
  • HBXIP
• Synonyms gene name
  • hepatitis B virus x interacting protein
• Synonyms
  • XIP
  • MGC71071
• Synonyms name
  • HBx-interacting protein
  • hepatitis B virus x-interacting protein (9.6kD)
• GenBank acession
  • AF029890
• Locus
  1p13.3
• Discovery year
  2002-01-10
• Entrez gene record
  10542
• Pubmed identfication
  • 9499022
  • 22980980
• RefSeq identity
  • NM_006402
• Classification
  • Ragulator complex
• VEGA ID
  OTTHUMG00000011568

Gene info

• Identity
  HGNC:18118
• Gene
  RSF1
• Long gene name
  remodeling and spacing factor 1
• Synonyms gene
  • HBXAP
• Synonyms gene name
  • hepatitis B virus x associated protein
• Synonyms
  • XAP8
  • RSF-1
  • p325
• GenBank acession
  • AF380176
  • AF227948
• Locus
  11q14.1
• Discovery year
  2002-02-12
• Entrez gene record
  51773
• Pubmed identfication
  • 11788598
  • 12972596
• RefSeq identity
  • NM_016578
• Classification
  • PHD finger proteins
• VEGA ID
  OTTHUMG00000150433

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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