Hepatitis B virus X protein Antibody, ALEXA FLUOR 488
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Catalog numberbs-2147R-A488
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PricePlease ask
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Size100ul
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Long nameHepatitis B virus X protein Antibody, ALEXA FLUOR 488 Conjugated
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Also known asAnti-Hepatitis B virus X protein PAb ALEXA FLUOR 488
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 488
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenHepatitis B virus X protein
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SpecificityThis is a highly specific antibody against Hepatitis B virus X protein.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range10-60/210
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SourceKLH conjugated synthetic peptide derived from Hepatitis B virus X protein
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityVirus
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Cross reactive species detailsHepatitis B virus
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Background of the antigenMultifunctional protein that may modulate protein degradation pathways, apoptosis, transcription, signal transduction, cell cycle progress, and genetic stability by directly or indirectly interacting with hosts factors. Does not seem to be essential for HBV infection. May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma). Most of cytosolic activities involve modulation of cytosolic calcium. The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted. By binding to human DDB1, may affect cell viability and stimulate genome replication. May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential. May also modulate apoptosis by binding human CFLAR, a key regulator of the death-inducing signaling complex (DISC). Moderately stimulates transcription of many different viral and cellular transcription elements. Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT. May bind bZIP transcription factors like CREB1 (By similarity).
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission499nm/519nm
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SynonymsHBX; pre-X protein; HB-X; X protein; HBV X protein; X protein [Hepatitis B virus].
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PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Hepatitis B virus X protein has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor
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DescriptionHepatitis a, b, c, d, e recombinant surface viral antigens to genotype 1, 2, 3, 4, 5 are used for antibody production to make diagnostic poly or monoclonal antibodies. Hepatitis is a disease of the liver characterized by the presence of inflammatory cells in the tissue of the organ. Hepatitis may occur without symptoms, but can lead to jaundice (a yellow discoloration of the skin, mucous membranes, and conjunctiva of the eyes), poor appetite, and fatigue. Depending on the cause, hepatitis can manifest either as an acute or as a chronic disease.
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French translationanticorps
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Gene target
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Gene symbolLAMTOR5P1, LAMTOR5, RSF1
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Short nameAnti-Hepatitis B virus X protein
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 488
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SpeciesVirus, Viruses
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Alternative nameHepatitis B virus X protein Antibody, ALEXA FLUOR 488
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Alternative techniqueantibodies
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Virushepatitis
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Gene info
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Identity
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Gene
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Long gene namelate endosomal/lysosomal adaptor, MAPK and MTOR activator 5 pseudogene 1
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Synonyms gene
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Synonyms gene name
- hepatitis B virus x interacting protein pseudogene 1
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Synonyms
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Synonyms name
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Locus
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Discovery year2010-06-17
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelate endosomal/lysosomal adaptor, MAPK and MTOR activator 5
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Synonyms gene
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Synonyms gene name
- hepatitis B virus x interacting protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-01-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ragulator complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameremodeling and spacing factor 1
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Synonyms gene
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Synonyms gene name
- hepatitis B virus x associated protein
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-02-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PHD finger proteins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data