-
Products_type
Antibody
-
Products_short_name
[GCGR / Glucagon Receptor]
-
Products_name_syn
[Anti-GCGR / Glucagon Receptor Antibody (N-Terminus) IHC-plus; GCGR; GL-R; Glucagon receptor; GGR; Human GCGR; Glucagon Receptor]
-
Other_names
[glucagon receptor; Glucagon receptor; glucagon receptor; glucagon receptor]
-
Products_gene_name
[GCGR]
-
Other_gene_names
[GCGR; GCGR; GGR; GL-R; GL-R]
-
Clonality
Polyclonal
-
Reactivity
Gibbon, Human Predicted Reactivity: Gorilla, Monkey, Bovine, Dog, Hamster, Horse (at least 90% immunogen sequence identity)
-
Specificity
Human Glucagon Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
-
Purity
Immunoaffinity Purified
-
Form
PBS, 0.1% sodium azide.
-
Concentration
1 mg/ml
-
Storage_stability
Long term: -70 degree C; Short term: +4 degree C
-
Tested_application
Immunohistochemistry (IHC - Paraffin)
-
Description
Glucagon gene and the glucagon like peptide or GLP1 gene are peptide hormones, produced by alpha cells of the pancreas to raise the concentration of glucose in the blood as opposite of insulin, which lowers the glucose. Anti human glucagon and glp1 antibodies are used to study diabetes. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Group
Polyclonals and antibodies
-
About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
Latin name
Oryctolagus cuniculus
-
Gene target
-
Gene symbol
GCGR
-
Short name
Rabbit Polyclonal GCGR / Glucagon Receptor
-
Technique
Polyclonal, Rabbit, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
-
Host
Rabbit, Rabbits
-
Species
Human, Humans
-
Alternative name
production species: rabbit polyclonal to H. sapiens gluca this GO n receptor / Glucagon Receptor
-
Alternative technique
polyclonals, rabbit-anti
-
Alternative to gene target
gluca this GO n receptor, GGR and GL-R, GCGR and IDBG-227533 and ENSG00000215644 and 2642, peptide hormone binding, Plasma membranes, Gcgr and IDBG-214830 and ENSMUSG00000025127 and 14527, BT.27844 and IDBG-642400 and ENSBTAG00000003786 and 515433
-
