Mouse Monoclonal [clone MN-1] (IgG) to Human MSLN / Mesothelin
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Catalog numberMBS249172
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PricePlease ask
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Size0.05 mg
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Products_typeAntibody
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Products_short_name[MSLN / Mesothelin]
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Products_name_syn[Anti-MSLN / Mesothelin Antibody (Extracellular Domain, clone MN-1) IHC-plus; MSLN; CAK1 antigen; MPF; SMRP; Mesothelin; CAK1; Human MSLN; Mesothelin]
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Other_names[mesothelin isoform 2 preproprotein; Mesothelin; mesothelin; CAK1 antigen; megakaryocyte potentiating factor; soluble MPF mesothelin related protein; pre-pro-megakaryocyte-potentiating factor; mesothelin; CAK1 antigen; Pre-pro-megakaryocyte-potentiating factorCleaved into the following 2 chains:Megakaryocyte-potentiating factor; MPF; Mesothelin, cleaved form]
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Products_gene_name[MSLN]
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Other_gene_names[MSLN; MSLN; MPF; SMRP; MPF; MPF]
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ClonalityMonoclonal
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Clone[MN-1]
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ReactivityHuman
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SpecificityCross reactivity with homologues from other sources has not been tested.
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PurityProtein A Purified
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Form0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide, sterile filtered
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Concentration1 mg/ml
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Storage_stabilityShort term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
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Tested_applicationImmunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutImmunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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Gene target
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Gene symbolMSLN, CA9, GYPA, MN1, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1
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Short nameMouse Monoclonal [clone MN-1] (IgG) MSLN / Mesothelin
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TechniqueMouse monoclonal, Mouse, IgG, IgGs, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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HostMouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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IsotypeIgG, IgG
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SpeciesHuman, Humans, Mouses
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Alternative nameMouse monoclonal [clonality MN-1] (Immunoglobulin G) to H. sapiens mesothelin / Mesothelin
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Alternative techniquemurine, immunoglobulins
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Alternative to gene targetmesothelin, MPF and SMRP, MSLN and IDBG-8270 and ENSG00000102854 and 10232, protein binding, Extracellular, Msln and IDBG-152832 and ENSMUSG00000063011 and 56047, MSLN and IDBG-634054 and ENSBTAG00000000177 and 516237
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Clone nameMN-1
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Gene info
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Identity
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Gene
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Long gene namemesothelin
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-11-22
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecarbonic anhydrase 9
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Synonyms gene name
- carbonic anhydrase IX
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-04-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Carbonic anhydrases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameglycophorin A (MNS blood group)
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Synonyms gene
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Synonyms gene name
- glycophorin A (includes MN blood group)
- glycophorin A (MN blood group)
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Blood group antigens
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameMN1 proto-oncogene, transcriptional regulator
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Synonyms gene
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Synonyms gene name
- meningioma chromosome region
- meningioma (disrupted in balanced translocation) 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-06-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 8-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 7-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family