Flk-1 Receptor Tyrosine Kinase (KDR, VEGFR2) (Biotin) Antibody

• Catalog number
  GEN600440
• Price
  Please ask
• Size
  100ug

• Also known as
  Flk-1 Receptor Tyrosine Kinase
• Other names
  N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG
• Clone
  7C29
• Host organism
  Rat (Rattus norvegicus)
• Source organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes mouse FLK13-Mb. Reacts specifically with human FLK-1/VEGFR-2/KDR. No crossreactivity with VGFR-1/FLT-1 or FLT-4.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Purified by immunoaffinity chromatography.
• Form Appearance
  Supplied as a liquid in 100mM Tris, pH 7.5, 0.2% BSA, 0.05% sodium azide, before the addition of glycerol to 40%. Labeled with Biotin.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage, For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 6 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested applications
  ELISA (EL/EIA)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Conjugation
  Biotinylated
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  Flk-1   Receptor   Tyrosine   Kinase   KDR   VEGFR2  
• Gene symbol
  KDR
• Short name
  Flk-1 Receptor Tyrosine Kinase (KDR, VEGFR2) ( ) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Label
  Biotin
• Alternative name
  Anti-Flk-1 Receptor Tyrosine Kinase (KDR, VEGFR2) (Biotin)
• Alternative technique
  antibodies
• Alternative to gene target
  kinase insert domain receptor (a type III receptor tyrosine kinase), CD309 and FLK1 and VEGFR and VEGFR2, KDR and IDBG-19161 and ENSG00000128052 and 3791, transferase activity, nuclei, Kdr and IDBG-172240 and ENSMUSG00000062960 and 16542, KDR and IDBG-642352 and ENSBTAG00000000782 and 407170

Gene info

• Identity
  HGNC:6307
• Gene
  KDR
• Long gene name
  kinase insert domain receptor
• Synonyms gene name
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
• Synonyms
  • FLK1
  • VEGFR
  • VEGFR2
  • CD309
• Synonyms name
  • vascular endothelial growth factor receptor 2
  • fetal liver kinase 1
• GenBank acession
  • AF035121
• Locus
  4q12
• Discovery year
  1991-07-10
• Entrez gene record
  3791
• Pubmed identfication
  • 1417831
• Classification
  • Receptor tyrosine kinases
  • CD molecules
  • I-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000128734
• Locus Specific Databases
  • The Globin Gene Server
  • LRG_1198

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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