Lysophosphatidic Acid Receptor 2 (EDG-4) - Control Lysate
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Catalog numberX1219C
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PricePlease ask
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Size100uL
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CategoryOther Reagents
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Long descriptionEDG4 (LPA2) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG4 is lysophospholipid. There are 6 known members of the EDG receptor family and they are implicated in mediating growthrelated effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor and leukocyte containing tissues.
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Antibody come fromn/a
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Other descriptionProvided in 10% glycerol, 0.063 M Tris-HCl (pH 6.8), 2% SDS and 0.002% bromophenol blue, 5% 2-mercaptoethanol.
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Clonenot specified
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Antigen antibody binding interactionLysophosphatidic Acid Receptor 2 (EDG-4) - Control Lysate
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Antibody is raised insee techfile
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Antibody s reacts withsee techfile
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Antibody s reacts with these speciesThis antibody doesn't cross react with other species
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Antibody s specificityNo Data Available
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ApplicationWestern Blot
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Antibody s suited forFor use as a positive control with Exalpha's EDG4 (NT) monoclonal antibody (Cat. No. C180M) for Western blot analysis. Will not work with EDG4 (CT) antibody (Cat. No. C181M).. Grown in RH7 cells.
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Storage-20ºC
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Relevant referencesno information yet
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Protein numbersee ncbi
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WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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DescriptionIsotype or positive controls by peptides, antibodies and deactivated samples. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolLPAR2, S1PR5, S1PR1, MIR1302-4, PIRC18, PIRC16, SNORD114-4, MIR941-4
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Short nameLysophosphatidic Acid Receptor 2 (EDG-4) - Control Lysate
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TechniqueControl, controls
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Isotypenot specified
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Labelunlabeled
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Alternative nameLysophosphatidic Acid Receptor 2 (EDG-4) - reference Lysate
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Alternative techniquecontrols
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Tissuecontrol, lysate
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Viruslysate
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Gene info
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Identity
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Gene
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Long gene namelysophosphatidic acid receptor 2
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Synonyms gene
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Synonyms gene name
- endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Lysophosphatidic acid receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesphingosine-1-phosphate receptor 5
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Synonyms gene
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Synonyms gene name
- endothelial differentiation, sphingolipid G-protein-coupled receptor, 8
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-01-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Sphingosine 1-phosphate receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesphingosine-1-phosphate receptor 1
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Synonyms gene
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Synonyms gene name
- endothelial differentiation, sphingolipid G-protein-coupled receptor, 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-05-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Sphingosine 1-phosphate receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1302-4
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1302 family
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 18
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 16
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 114-4
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Synonyms
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Locus
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Discovery year2006-09-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene namemicroRNA 941-4
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Synonyms gene
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Synonyms
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Locus
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Discovery year2007-10-24
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNAs
