p70 S6 Kinase alpha Antibody (RPS6KB1)

• Catalog number
  F48466-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  p70 S6 Kinase alpha (RPS6KB1)
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
• Notes
  Titration of the S6K antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This S6K antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P23443
• Purity
  Purified
• Description
  This gene encodes a member of the RSK (ribosomal s6 kinase) family of serine/threonine kinases. This kinase phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Inhibition of the S6K1 protein, or a lack of it, slows the production of adipose (fat) cells by disrupting and retarding the initial commitment stage of their formation. [Wiki]
• Immunogen
  A portion of amino acids 277-306 from the human protein was used as the immunogen for this S6K antibody.
• Storage
  Aliquot the S6K antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Additional description
  The Anti-p70 S6 Kinase alpha (RPS6KB1) is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  p70   Kinase   alpha   RPS6KB1  
• Gene symbol
  RPS6KB1
• Short name
  Anti-p70 S6 Kinase alpha (RPS6KB1)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to p70 S6 Kinase alpha (RPS6KB1)
• Alternative technique
  antibodies
• Alternative to gene target
  ribosomal protein S6 kinase, 70kDa, polypeptide 1, p70 S6KA and p70-alpha and p70-S6K and p70(S6K)-alpha and PS6K and S6K and S6K-beta-1 and S6K1 and STK14A, RPS6KB1 and IDBG-61938 and ENSG00000108443 and 6198, transferase activity, nuclei, Rps6kb1 and IDBG-206895 and ENSMUSG00000020516 and 72508, RPS6KB1 and IDBG-629797 and ENSBTAG00000016851 and 404181

Gene info

• Identity
  HGNC:10436
• Gene
  RPS6KB1
• Long gene name
  ribosomal protein S6 kinase B1
• Synonyms gene
  • STK14A
• Synonyms gene name
  • ribosomal protein S6 kinase, 70kD, polypeptide 1
• Synonyms
  • S6K1
  • p70(S6K)-alpha
  • PS6K
  • S6K
• GenBank acession
  • M60724
• Locus
  17q23.1
• Discovery year
  1994-07-11
• Entrez gene record
  6198
• Pubmed identfication
  • 1922062
• RefSeq identity
  • NM_003161
• Classification
  • AGC family kinases
• VEGA ID
  OTTHUMG00000150642

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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