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RNF126 Polyclonal Antibody

RNF126 Polyclonal Antibody is available 2 times from Bioma labs

CAC07882 | RNF126 Polyclonal Antibody size: 100 μg | 445.23 USD

Catalog number CAC07882
Supplier bioma
Price 445.23 USD
Size 100 μg
1. Gene info
Identity21151
GeneRNF126
Synonyms
GenBank acession
Locus19p13.3
Discovery year2003-05-21
RefSeq identity
Havana BLAST/BLATOTTHUMG00000180592
MeSH Data
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200

CAC07882 | RNF126 Polyclonal Antibody size: 50 μg | 272.02 USD

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Other name E3 ubiquitin-protein ligase RNF126,RING finger protein 126,RNF126
Clonality Polyclonal
Purity Protein G purified, >95%
Estimated production time 3-7 business days
Raised in Rabbit
NCBI number Please refer to NCBI
Gene number Please refer to GenBank
Immunogen Recombinant Human E3 ubiquitin-protein ligase RNF126 protein (39-225AA)
Protein number Q9BV68
Notes For research use only. Not for diagnostic procedures.
Use before 1 year
Storage recommendation Aliquot and store at -20°C. Minimize freezing and thawing.
Shipping requirements Blue ice
Verified reactivity Human, Mouse
Supplementary information E3 ubiquitin-protein ligase that regulates several biological processes through ubiquitination of various target proteins. Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates. Through their polyubiquitination, may play a role in the endosomal sorting and degradation of several membrane receptors including EGFR, FLT3, MET and CXCR4. May also be part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome. May provide the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the mislocalized proteins and their targeting to the proteasome (PubMed:24981174). May also play a role in the endosomal recycling of IGF2R, the cation-independent mannose-6-phosphate receptor (PubMed:24275455). By ubiquitinating CDKN1A/p21 and targeting it for degradation, may also promote cell proliferation (PubMed:23026136). May monoubiquitinate AICDA (PubMed:23277564).
Verified applications ELISA,WB,IHC,IF. Recommended dilution:WB:1:500-1:5000,IHC:1:20-1:200,IF:1:50-1:200
Properties If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
French translation anticorps
Gene targetRNF126
Short name RNF126 Polyclonal Antibody
Technique Polyclonal, Antibody
Alternative name RNF126 polyclonal (Antibody to)
Alternative technique polyclonals
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RNF126 Polyclonal Antibody size: 100 μg - Gentaur.com
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